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Eylea and Circulatory collapse - a phase IV clinical study of FDA data

Summary:

Circulatory collapse is reported as a side effect among people who take Eylea (aflibercept), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Diclofenac, and have Retinal vessel occlusion.

The phase IV clinical study analyzes which people have Circulatory collapse when taking Eylea. It is created by eHealthMe based on reports of 27,819 people who have side effects when taking Eylea from the FDA, and is updated regularly.

What is Eylea?

Eylea has active ingredients of aflibercept. It is often used in macular degeneration. eHealthMe is studying from 27,868 Eylea users. Check the latest studies of Eylea.

What is Circulatory collapse?

Circulatory collapse is found to be associated with 1,122 drugs and 1,403 conditions by eHealthMe. Check the latest studies of Circulatory collapse.

On Jul, 30, 2026

27,819 people reported to have side effects when taking Eylea.
Among them, 11 people (0.04%) have Circulatory collapse.

Could Eylea cause Circulatory collapse?

Among these 11 people:

How long have people been on Eylea when they have Circulatory collapse? *

  • < 1 month: 100 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Circulatory collapse when taking Eylea? *

  • female: 33.33 %
  • male: 66.67 %

What is the age of people who have Circulatory collapse when taking Eylea? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 0.0 %
  • 60+: 100 %

What are other drugs people take besides Eylea? *

  1. Multaq: 1 person, 9.09%
  2. Diclofenac: 1 person, 9.09%

What are other side effects people have besides Circulatory collapse? *

  1. Headache (pain in head): 4 people, 36.36%
  2. Pulmonary Embolism (blockage of the main artery of the lung): 2 people, 18.18%
  3. Panic Disorder: 2 people, 18.18%
  4. Chills (felling of cold): 2 people, 18.18%
  5. Influenza Like Illness: 2 people, 18.18%
  6. Cough: 2 people, 18.18%
  7. Death: 2 people, 18.18%
  8. Dizziness: 2 people, 18.18%
  9. Stress And Anxiety: 2 people, 18.18%
  10. Fatigue (feeling of tiredness): 2 people, 18.18%

What are the existing conditions these people have? *

  1. Retinal Vessel Occlusion (a blockage in one of the small arteries): 3 people, 27.27%
  2. Age-Related Macular Degeneration: 1 person, 9.09%

* Approximation only. Some reports may have incomplete information.

Do you take Eylea and have Circulatory collapse?

- Check whether Circulatory collapse is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Eylea:

Circulatory collapse treatments and more:

How severe was Circulatory collapse and when was it recovered:

Expand to all the drugs that have ingredients of aflibercept:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Eylea:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Circulatory collapse:

Browse all the conditions that are associated with Circulatory collapse:

How the study uses the data?

The study uses data from the FDA. It is based on aflibercept (the active ingredients of Eylea) and Eylea (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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