Eylea and Constipation - a phase IV clinical study of FDA data

Summary:

Constipation is reported as a side effect among people who take Eylea (aflibercept), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Ibrance, and have Breast cancer female.

The phase IV clinical study analyzes which people have Constipation when taking Eylea. It is created by eHealthMe based on reports of 27,819 people who have side effects when taking Eylea from the FDA, and is updated regularly.

What is Eylea?

Eylea has active ingredients of aflibercept. It is often used in macular degeneration. eHealthMe is studying from 27,868 Eylea users. Check the latest studies of Eylea.

What is Constipation?

Constipation is found to be associated with 3,005 drugs and 4,602 conditions by eHealthMe. Check the latest studies of Constipation.

On Apr, 05, 2026

27,819 people reported to have side effects when taking Eylea.
Among them, 20 people (0.07%) have Constipation.

Among these 20 people:

How long have people been on Eylea when they have Constipation? *

What is the gender of people who have Constipation when taking Eylea? *

female: 69.23 %
male: 30.77 %

What is the age of people who have Constipation when taking Eylea? *

What are other drugs people take besides Eylea? *

What are other side effects people have besides Constipation? *

Fatigue (feeling of tiredness): 6 people, 30.00%
Headache (pain in head): 5 people, 25.00%
Insomnia (sleeplessness): 4 people, 20.00%
Nasopharyngitis (inflammation of the nasopharynx): 4 people, 20.00%
Dyspnea (difficult or laboured breathing): 4 people, 20.00%
Appetite - Decreased (decreased appetite occurs when you have a reduced desire to eat): 4 people, 20.00%
Weight Decreased: 4 people, 20.00%
Generalised Oedema (swelling all over the body): 3 people, 15.00%
Hair Loss: 3 people, 15.00%
Pain Of Skin: 3 people, 15.00%

What are the existing conditions these people have? *

Breast Cancer Female: 4 people, 20.00%
Hypercalcaemia (elevated calcium (ca+) level in the blood): 3 people, 15.00%
Diabetic Retinal Oedema (excessive build-up of fluid in the retina due to diabetes): 2 people, 10.00%
Stomatitis (inflammation of mucous membrane of mouth): 1 person, 5.00%
Retinal Vessel Occlusion (a blockage in one of the small arteries): 1 person, 5.00%
Prostate Cancer: 1 person, 5.00%
Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 1 person, 5.00%
Pain: 1 person, 5.00%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 1 person, 5.00%
Multiple Myeloma (cancer of the plasma cells): 1 person, 5.00%

* Approximation only. Some reports may have incomplete information.

Do you take Eylea and have Constipation?

- Check whether Constipation is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Eylea:

Eylea (27,868 reports)

Constipation treatments and more:

Constipation (337,873 reports)

Browse all side effects of Eylea:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Constipation:

Constipation (3,005 drugs)

Browse all the conditions that are associated with Constipation:

Constipation (4,602 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on aflibercept (the active ingredients of Eylea) and Eylea (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.