Eylea and Low thyroid - a phase IV clinical study of FDA data

Summary:

Low thyroid is reported as a side effect among people who take Eylea (aflibercept), especially for people who are female, 60+ old, also take Movicol, and have High blood pressure.

The phase IV clinical study analyzes which people have Low thyroid when taking Eylea. It is created by eHealthMe based on reports of 27,819 people who have side effects when taking Eylea from the FDA, and is updated regularly.

What is Eylea?

Eylea has active ingredients of aflibercept. It is often used in macular degeneration. eHealthMe is studying from 27,868 Eylea users. Check the latest studies of Eylea.

What is Low thyroid?

Low thyroid (abnormally low thyroid hormone production) is found to be associated with 2,759 drugs and 2,618 conditions by eHealthMe. Check the latest studies of Low thyroid.

On Nov, 11, 2025

27,819 people reported to have side effects when taking Eylea.
Among them, 11 people (0.04%) have Low thyroid.

Among these 11 people:

What is the gender of people who have Low thyroid when taking Eylea? *

female: 83.33 %
male: 16.67 %

What is the age of people who have Low thyroid when taking Eylea? *

What are other drugs people take besides Eylea? *

What are other side effects people have besides Low thyroid? *

High Blood Pressure: 6 people, 54.55%
Dizziness: 5 people, 45.45%
Diarrhea: 4 people, 36.36%
Rashes (redness): 4 people, 36.36%
Anaemia (lack of blood): 4 people, 36.36%
Haemorrhoids (a swollen vein or group of veins in the region of the anus): 4 people, 36.36%
Chronic Kidney Disease: 4 people, 36.36%
Cataract (clouding of the lens inside the eye): 4 people, 36.36%
Tinnitus (a ringing in the ears): 4 people, 36.36%
Fall: 3 people, 27.27%

What are the existing conditions these people have? *

High Blood Pressure: 4 people, 36.36%
Diabetic Retinopathy (damage to the retina caused by complications of diabetes): 3 people, 27.27%
Transient Ischaemic Attack (a transient episode of neurologic dysfunction caused by ischemia (loss of blood flow)): 2 people, 18.18%
Retinal Vessel Occlusion (a blockage in one of the small arteries): 2 people, 18.18%
Rashes (redness): 2 people, 18.18%
Macular Oedema (fluid and protein deposits collect on or under the macula of the eye (a yellow central area of the retina) and causes it to thicken): 2 people, 18.18%
Diabetic Retinal Oedema (excessive build-up of fluid in the retina due to diabetes): 2 people, 18.18%
Diabetes: 2 people, 18.18%
Vitreous Haemorrhage (intraocular (inside the eye) bleeding): 1 person, 9.09%
Vision Blurred: 1 person, 9.09%

* Approximation only. Some reports may have incomplete information.

Do you take Eylea and have Low thyroid?

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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Eylea:

Eylea (27,868 reports)

Low thyroid treatments and more:

Low thyroid (168,013 reports)

Browse all side effects of Eylea:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Low thyroid:

Low thyroid (2,759 drugs)

Browse all the conditions that are associated with Low thyroid:

Low thyroid (2,618 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on aflibercept (the active ingredients of Eylea) and Eylea (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.