Eylea and Pulmonary oedema - a phase IV clinical study of FDA data

Summary:

Pulmonary oedema is reported as a side effect among people who take Eylea (aflibercept), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Carbamazepine, and have Asthma.

The phase IV clinical study analyzes which people have Pulmonary oedema when taking Eylea. It is created by eHealthMe based on reports of 27,819 people who have side effects when taking Eylea from the FDA, and is updated regularly.

What is Eylea?

Eylea has active ingredients of aflibercept. It is often used in macular degeneration. eHealthMe is studying from 27,868 Eylea users. Check the latest studies of Eylea.

What is Pulmonary oedema?

Pulmonary oedema (fluid accumulation in the lungs) is found to be associated with 1,849 drugs and 1,967 conditions by eHealthMe. Check the latest studies of Pulmonary oedema.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 26, 2026

27,819 people reported to have side effects when taking Eylea.
Among them, 23 people (0.08%) have Pulmonary oedema.

Among these 23 people:

How long have people been on Eylea when they have Pulmonary oedema? *

What is the gender of people who have Pulmonary oedema when taking Eylea? *

female: 27.27 %
male: 72.73 %

What is the age of people who have Pulmonary oedema when taking Eylea? *

What are other drugs people take besides Eylea? *

Albuterol: 7 people, 30.43%
Simvastatin: 7 people, 30.43%
Omeprazole: 7 people, 30.43%
Aspirin: 7 people, 30.43%
Lucentis: 7 people, 30.43%
Avastin: 7 people, 30.43%
Carbamazepine: 7 people, 30.43%
Amitriptyline Hydrochloride: 4 people, 17.39%
Amlodipine: 4 people, 17.39%
Tamsulosin: 3 people, 13.04%

What are other side effects people have besides Pulmonary oedema? *

Dyspnea (difficult or laboured breathing): 9 people, 39.13%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 8 people, 34.78%
Abdominal Pain Upper: 7 people, 30.43%
Pulmonary Thrombosis (scarring in the lungs): 7 people, 30.43%
Drug Ineffective: 7 people, 30.43%
Eye Haemorrhage (bleeding in the eye): 7 people, 30.43%
Fall: 7 people, 30.43%
Fatigue (feeling of tiredness): 7 people, 30.43%
High Blood Cholesterol: 7 people, 30.43%
Cardiac Failure Congestive: 7 people, 30.43%

What are the existing conditions these people have? *

Pain: 7 people, 30.43%
Diabetic Retinal Oedema (excessive build-up of fluid in the retina due to diabetes): 7 people, 30.43%
Choroidal Neovascularisation (creation of new blood vessels in vascular layer of eye): 7 people, 30.43%
Asthma: 7 people, 30.43%
High Blood Pressure: 2 people, 8.70%
Diabetic Retinopathy (damage to the retina caused by complications of diabetes): 2 people, 8.70%
Diabetes: 2 people, 8.70%
Parkinson's Disease: 1 person, 4.35%
Macular Oedema (fluid and protein deposits collect on or under the macula of the eye (a yellow central area of the retina) and causes it to thicken): 1 person, 4.35%
Keratitis (eye's cornea, the front part of the eye, becomes inflamed): 1 person, 4.35%

* Approximation only. Some reports may have incomplete information.

Do you take Eylea and have Pulmonary oedema?

- Check whether Pulmonary oedema is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Eylea:

Eylea (27,868 reports)

Pulmonary oedema treatments and more:

Pulmonary oedema (53,624 reports)

Browse all side effects of Eylea:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Pulmonary oedema:

Pulmonary oedema (1,850 drugs)

Browse all the conditions that are associated with Pulmonary oedema:

Pulmonary oedema (1,967 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on aflibercept (the active ingredients of Eylea) and Eylea (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.