Ezetimibe and Sjogren syndrome - a phase IV clinical study of FDA data

Summary:

Sjogren syndrome is reported as a side effect among people who take Ezetimibe (ezetimibe), especially for people who are female, 60+ old, have been taking the drug for 1 - 6 months also take Folic Acid, and have Rheumatoid arthritis.

The phase IV clinical study analyzes which people have Sjogren syndrome when taking Ezetimibe. It is created by eHealthMe based on reports of 30,221 people who have side effects when taking Ezetimibe from the FDA, and is updated regularly.

What is Ezetimibe?

Ezetimibe has active ingredients of ezetimibe. It is often used in high blood cholesterol. eHealthMe is studying from 30,849 Ezetimibe users. Check the latest studies of Ezetimibe.

What is Sjogren syndrome?

Sjogren syndrome (a disease that causes dryness in the mouth and eyes) is found to be associated with 615 drugs and 964 conditions by eHealthMe. Check the latest studies of Sjogren syndrome.



On Jul, 08, 2026

30,221 people reported to have side effects when taking Ezetimibe.
Among them, 36 people (0.12%) have Sjogren syndrome.

Could Ezetimibe cause Sjogren syndrome?

Among these 36 people:

How long have people been on Ezetimibe when they have Sjogren syndrome? *

  • < 1 month: 0.0 %
  • 1 - 6 months: 100 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Sjogren syndrome when taking Ezetimibe? *

  • female: 93.1 %
  • male: 6.9 %

What is the age of people who have Sjogren syndrome when taking Ezetimibe? *

  • 0-1: 0.0 %
  • 2-9: 3.85 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 30.77 %
  • 60+: 65.38 %

What are other drugs people take besides Ezetimibe? *

  1. Bactrim: 10 people, 27.78%
  2. Folic Acid: 10 people, 27.78%
  3. Lipitor: 7 people, 19.44%
  4. Simvastatin: 7 people, 19.44%
  5. Vitamin D3: 7 people, 19.44%
  6. Zyrtec: 6 people, 16.67%
  7. Meclizine: 6 people, 16.67%
  8. Lescol Xl: 6 people, 16.67%
  9. Levaquin: 6 people, 16.67%
  10. Macrobid: 6 people, 16.67%

What are other side effects people have besides Sjogren syndrome? *

  1. Dry Mouth: 9 people, 25.00%
  2. Fatigue (feeling of tiredness): 9 people, 25.00%
  3. Ear Haemorrhage (bleeding from ear): 9 people, 25.00%
  4. Dizziness: 9 people, 25.00%
  5. Stomatitis (inflammation of mucous membrane of mouth): 9 people, 25.00%
  6. High Blood Pressure: 9 people, 25.00%
  7. Muscle Spasms (muscle contraction): 8 people, 22.22%
  8. Fall: 8 people, 22.22%
  9. Pain: 8 people, 22.22%
  10. Hot Flush (sudden feelings of heat): 8 people, 22.22%

What are the existing conditions these people have? *

  1. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 7 people, 19.44%
  2. Osteoporosis (bones weak and more likely to break): 6 people, 16.67%
  3. Primary Myelofibrosis (primary disorder of the bone marrow): 4 people, 11.11%
  4. Polycythaemia Vera (blood disorder in which the bone marrow makes too many red blood cells): 4 people, 11.11%
  5. Diabetes: 4 people, 11.11%
  6. Ill-Defined Disorder: 3 people, 8.33%
  7. Cataplexy (loss of muscle tone accompanied by full conscious awareness): 2 people, 5.56%
  8. Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 2 people, 5.56%
  9. Gastric Disorder (disease of stomach): 2 people, 5.56%
  10. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 2 people, 5.56%

* Approximation only. Some reports may have incomplete information.

Do you take Ezetimibe and have Sjogren syndrome?

- Check whether Sjogren syndrome is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Ezetimibe:

Sjogren syndrome treatments and more:

How severe was Sjogren syndrome and when was it recovered:

Expand to all the drugs that have ingredients of ezetimibe:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Ezetimibe:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Sjogren syndrome:

Browse all the conditions that are associated with Sjogren syndrome:


How the study uses the data?

The study uses data from the FDA. It is based on ezetimibe (the active ingredients of Ezetimibe) and Ezetimibe (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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