Factive and Depression - a phase IV clinical study of FDA data

Summary:

Depression is reported as a side effect among people who take Factive (gemifloxacin mesylate), especially for people who are female, 60+ old, also take Rocephin, and have Infection.

The phase IV clinical study analyzes which people have Depression when taking Factive. It is created by eHealthMe based on reports of 1,420 people who have side effects when taking Factive from the FDA, and is updated regularly.

What is Factive?

Factive has active ingredients of gemifloxacin mesylate. eHealthMe is studying from 1,430 Factive users. Check the latest studies of Factive.

What is Depression?

Depression is found to be associated with 3,222 drugs and 4,063 conditions by eHealthMe. Check the latest studies of Depression.

On Jul, 31, 2025

1,420 people reported to have side effects when taking Factive.
Among them, 14 people (0.99%) have Depression.

Among these 14 people:

What is the gender of people who have Depression when taking Factive? *

female: 100 %
male: 0.0 %

What is the age of people who have Depression when taking Factive? *

What are other drugs people take besides Factive? *

What are other side effects people have besides Depression? *

Osteoarthritis (a joint disease caused by cartilage loss in a joint): 10 people, 71.43%
Incontinence (lack of moderation or self-control): 8 people, 57.14%
Osteopenia (a condition where bone mineral density is lower than normal): 8 people, 57.14%
Meningioma (a diverse set of tumours arising from the meninges): 8 people, 57.14%
Pain: 8 people, 57.14%
Fatigue (feeling of tiredness): 8 people, 57.14%
Cardiac Failure Congestive: 8 people, 57.14%
Head Injury: 7 people, 50.00%
Eye Disorder: 7 people, 50.00%
Neuropathy Peripheral (surface nerve damage): 7 people, 50.00%

What are the existing conditions these people have? *

Pain: 2 people, 14.29%
Infection: 2 people, 14.29%
Osteoporosis (bones weak and more likely to break): 1 person, 7.14%
High Blood Cholesterol: 1 person, 7.14%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 1 person, 7.14%
Asthma: 1 person, 7.14%

* Approximation only. Some reports may have incomplete information.

Do you take Factive and have Depression?

- Check whether Depression is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Factive:

Factive (1,430 reports)

Depression treatments and more:

Depression (652,008 reports)

Browse all side effects of Factive:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Depression:

Depression (3,222 drugs)

Browse all the conditions that are associated with Depression:

Depression (4,063 conditions)

Related publications that referenced our studies

Pang, T., & Gudi, A., "Chest pain following the use of fluvoxamine in depression", Proceedings of Singapore Healthcare, 2018 Jan .
Pang, T., & Gudi, A., "Chest pain following the use of fluvoxamine in depression", Proceedings of Singapore Healthcare, 2018 Jan .

How the study uses the data?

The study uses data from the FDA. It is based on gemifloxacin mesylate (the active ingredients of Factive) and Factive (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.