Febuxostat and Cardiac failure acute - a phase IV clinical study of FDA data

Summary:

Cardiac failure acute is reported as a side effect among people who take Febuxostat (febuxostat), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Furosemide, and have Hyperuricaemia.

The phase IV clinical study analyzes which people have Cardiac failure acute when taking Febuxostat. It is created by eHealthMe based on reports of 9,653 people who have side effects when taking Febuxostat from the FDA, and is updated regularly.

What is Febuxostat?

Febuxostat has active ingredients of febuxostat. eHealthMe is studying from 9,693 Febuxostat users. Check the latest studies of Febuxostat.

What is Cardiac failure acute?

Cardiac failure acute is found to be associated with 680 drugs and 749 conditions by eHealthMe. Check the latest studies of Cardiac failure acute.

On Aug, 04, 2026

9,653 people reported to have side effects when taking Febuxostat.
Among them, 51 people (0.53%) have Cardiac failure acute.

Could Febuxostat cause Cardiac failure acute?

Among these 51 people:

How long have people been on Febuxostat when they have Cardiac failure acute? *

What is the gender of people who have Cardiac failure acute when taking Febuxostat? *

female: 37.5 %
male: 62.5 %

What is the age of people who have Cardiac failure acute when taking Febuxostat? *

What are other drugs people take besides Febuxostat? *

What are other side effects people have besides Cardiac failure acute? *

Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 6 people, 11.76%
Anaemia (lack of blood): 5 people, 9.80%
Neuropathy Peripheral (surface nerve damage): 5 people, 9.80%
Pneumonia: 5 people, 9.80%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 5 people, 9.80%
Renal Impairment (severely reduced kidney function): 5 people, 9.80%
Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets): 5 people, 9.80%
Dyspnea (difficult or laboured breathing): 5 people, 9.80%
Arrhythmias (irregular heartbeat): 5 people, 9.80%
Chest Pain: 4 people, 7.84%

What are the existing conditions these people have? *

Hyperuricaemia (level of uric acid in the blood that is abnormally high): 16 people, 31.37%
High Blood Pressure: 14 people, 27.45%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 7 people, 13.73%
Renal Cell Carcinoma (a kidney cancer): 6 people, 11.76%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 5 people, 9.80%
Hyperkalemia (damage to or disease of the kidney): 5 people, 9.80%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 5 people, 9.80%
High Blood Cholesterol: 4 people, 7.84%
Constipation: 4 people, 7.84%
Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 4 people, 7.84%

* Approximation only. Some reports may have incomplete information.

Do you take Febuxostat and have Cardiac failure acute?

- Check whether Cardiac failure acute is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Febuxostat:

Febuxostat (9,693 reports)

Browse all side effects of Febuxostat:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Cardiac failure acute:

Cardiac failure acute (680 drugs)

Browse all the conditions that are associated with Cardiac failure acute:

Cardiac failure acute (749 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on febuxostat (the active ingredients of Febuxostat) and Febuxostat (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.