Febuxostat and Hypercholesterolaemia aggravated - a phase IV clinical study of FDA data

Summary:

Hypercholesterolaemia aggravated is reported as a side effect among people who take Febuxostat (febuxostat), especially for people who are male, 60+ old, have been taking the drug for 1 - 6 months also take Crestor, and have Hyperuricaemia.

The phase IV clinical study analyzes which people have Hypercholesterolaemia aggravated when taking Febuxostat. It is created by eHealthMe based on reports of 9,653 people who have side effects when taking Febuxostat from the FDA, and is updated regularly.

What is Febuxostat?

Febuxostat has active ingredients of febuxostat. eHealthMe is studying from 9,693 Febuxostat users. Check the latest studies of Febuxostat.

What is Hypercholesterolaemia aggravated?

Hypercholesterolaemia aggravated (high levels of cholesterol in the blood) is found to be associated with 1,512 drugs and 508 conditions by eHealthMe. Check the latest studies of Hypercholesterolaemia aggravated.



On Jul, 29, 2026

9,653 people reported to have side effects when taking Febuxostat.
Among them, 46 people (0.48%) have Hypercholesterolaemia aggravated.

Could Febuxostat cause Hypercholesterolaemia aggravated?

Among these 46 people:

How long have people been on Febuxostat when they have Hypercholesterolaemia aggravated? *

  • < 1 month: 40.0 %
  • 1 - 6 months: 46.67 %
  • 6 - 12 months: 13.33 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Hypercholesterolaemia aggravated when taking Febuxostat? *

  • female: 23.68 %
  • male: 76.32 %

What is the age of people who have Hypercholesterolaemia aggravated when taking Febuxostat? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 5.26 %
  • 30-39: 2.63 %
  • 40-49: 26.32 %
  • 50-59: 15.79 %
  • 60+: 50.0 %

What are other drugs people take besides Febuxostat? *

  1. Crestor: 13 people, 28.26%
  2. Zetia: 12 people, 26.09%
  3. Belsomra: 11 people, 23.91%
  4. Dovato: 10 people, 21.74%
  5. Nizoral: 10 people, 21.74%
  6. Amoxicillin: 10 people, 21.74%
  7. Probenecid: 10 people, 21.74%
  8. Tivicay: 8 people, 17.39%
  9. Locoid: 7 people, 15.22%
  10. Prograf: 7 people, 15.22%

What are other side effects people have besides Hypercholesterolaemia aggravated? *

  1. Blood Alkaline Phosphatase Increased: 10 people, 21.74%
  2. Intervertebral Disc Protrusion (spinal disc protrusion): 10 people, 21.74%
  3. Dyslipidaemia (abnormal amount of lipids): 10 people, 21.74%
  4. Blood Urea Increased: 10 people, 21.74%
  5. Herpes Zoster: 10 people, 21.74%
  6. Enlarged Prostate: 10 people, 21.74%
  7. Insomnia (sleeplessness): 9 people, 19.57%
  8. Blood Creatinine Increased: 9 people, 19.57%
  9. High Blood Pressure: 8 people, 17.39%
  10. Asthma: 7 people, 15.22%

What are the existing conditions these people have? *

  1. Hyperuricaemia (level of uric acid in the blood that is abnormally high): 16 people, 34.78%
  2. Hiv Infection: 13 people, 28.26%
  3. High Blood Pressure: 13 people, 28.26%
  4. Insomnia (sleeplessness): 12 people, 26.09%
  5. Blood Uric Acid Increased: 7 people, 15.22%
  6. Seborrhoeic Dermatitis (a common, inflammatory skin condition that causes flaky, white to yellowish scales to form on oily areas such as the scalp): 5 people, 10.87%
  7. Iron Deficiency Anaemia: 4 people, 8.70%
  8. Gastritis (inflammation of stomach): 4 people, 8.70%
  9. Cardiac Failure: 4 people, 8.70%
  10. Osteoporosis (bones weak and more likely to break): 4 people, 8.70%

* Approximation only. Some reports may have incomplete information.

Do you take Febuxostat and have Hypercholesterolaemia aggravated?

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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Febuxostat:

Hypercholesterolaemia aggravated treatments and more:

How severe was Hypercholesterolaemia aggravated and when was it recovered:

Expand to all the drugs that have ingredients of febuxostat:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Febuxostat:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hypercholesterolaemia aggravated:

Browse all the conditions that are associated with Hypercholesterolaemia aggravated:


How the study uses the data?

The study uses data from the FDA. It is based on febuxostat (the active ingredients of Febuxostat) and Febuxostat (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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