Feldene and Joint swelling - a phase IV clinical study of FDA data

Summary:

Joint swelling is reported as a side effect among people who take Feldene (piroxicam), especially for people who are female, 60+ old, also take Lasix, and have Calcium deficiency.

The phase IV clinical study analyzes which people have Joint swelling when taking Feldene. It is created by eHealthMe based on reports of 3,850 people who have side effects when taking Feldene from the FDA, and is updated regularly.

What is Feldene?

Feldene has active ingredients of piroxicam. It is often used in arthritis. eHealthMe is studying from 3,913 Feldene users. Check the latest studies of Feldene.

What is Joint swelling?

Joint swelling is found to be associated with 2,120 drugs and 2,934 conditions by eHealthMe. Check the latest studies of Joint swelling.



On Jul, 08, 2026

3,850 people reported to have side effects when taking Feldene.
Among them, 61 people (1.58%) have Joint swelling.

Could Feldene cause Joint swelling?

Among these 61 people:

What is the gender of people who have Joint swelling when taking Feldene? *

  • female: 71.19 %
  • male: 28.81 %

What is the age of people who have Joint swelling when taking Feldene? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 2.08 %
  • 30-39: 2.08 %
  • 40-49: 2.08 %
  • 50-59: 10.42 %
  • 60+: 83.33 %

What are other drugs people take besides Feldene? *

  1. Lasix: 32 people, 52.46%
  2. Zometa: 31 people, 50.82%
  3. Elavil: 30 people, 49.18%
  4. Furosemide: 29 people, 47.54%
  5. Spironolactone: 29 people, 47.54%
  6. Coumadin: 27 people, 44.26%
  7. Crestor: 25 people, 40.98%
  8. Vioxx: 25 people, 40.98%
  9. Kenalog: 23 people, 37.70%
  10. Klor-Con: 22 people, 36.07%

What are other side effects people have besides Joint swelling? *

  1. Joint Pain: 49 people, 80.33%
  2. Pain: 37 people, 60.66%
  3. Stress And Anxiety: 34 people, 55.74%
  4. Depression: 33 people, 54.10%
  5. Intervertebral Disc Degeneration (spinal disc degeneration): 32 people, 52.46%
  6. Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 31 people, 50.82%
  7. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 30 people, 49.18%
  8. Anhedonia (inability to experience pleasure from activities usually found enjoyable): 30 people, 49.18%
  9. Fainting (loss of consciousness and postural tone): 30 people, 49.18%
  10. Bone Disorder: 29 people, 47.54%

What are the existing conditions these people have? *

  1. Metastases To Spine (cancer spreads to spine): 21 people, 34.43%
  2. Neoplasm Malignant (cancer tumour): 21 people, 34.43%
  3. Calcium Deficiency (lack of calcium): 21 people, 34.43%
  4. Lung Neoplasm (tumour of lung): 20 people, 32.79%
  5. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 11 people, 18.03%
  6. Depression: 10 people, 16.39%
  7. Multiple Myeloma (cancer of the plasma cells): 9 people, 14.75%
  8. Stable Angina (a constant chest pain): 8 people, 13.11%
  9. Arrhythmias (irregular heartbeat): 8 people, 13.11%
  10. High Blood Pressure: 8 people, 13.11%

* Approximation only. Some reports may have incomplete information.

Do you take Feldene and have Joint swelling?

- Check whether Joint swelling is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Feldene:

Joint swelling treatments and more:

How severe was Joint swelling and when was it recovered:

Expand to all the drugs that have ingredients of piroxicam:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Feldene:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Joint swelling:

Browse all the conditions that are associated with Joint swelling:

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on piroxicam (the active ingredients of Feldene) and Feldene (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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