Feldene and Sciatica - a phase IV clinical study of FDA data

Summary:

Sciatica is reported as a side effect among people who take Feldene (piroxicam), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Fosamax, and have Depression.

The phase IV clinical study analyzes which people have Sciatica when taking Feldene. It is created by eHealthMe based on reports of 3,850 people who have side effects when taking Feldene from the FDA, and is updated regularly.

What is Feldene?

Feldene has active ingredients of piroxicam. It is often used in arthritis. eHealthMe is studying from 3,913 Feldene users. Check the latest studies of Feldene.

What is Sciatica?

Sciatica (a set of symptoms including pain caused by general compression or irritation of one of five spinal nerve roots of each sciatic nerve) is found to be associated with 1,145 drugs and 1,431 conditions by eHealthMe. Check the latest studies of Sciatica.

On May, 01, 2026

3,850 people reported to have side effects when taking Feldene.
Among them, 33 people (0.86%) have Sciatica.

Among these 33 people:

How long have people been on Feldene when they have Sciatica? *

What is the gender of people who have Sciatica when taking Feldene? *

female: 77.42 %
male: 22.58 %

What is the age of people who have Sciatica when taking Feldene? *

What are other drugs people take besides Feldene? *

What are other side effects people have besides Sciatica? *

Joint Pain: 15 people, 45.45%
Muscle Spasms (muscle contraction): 13 people, 39.39%
Spinal Osteoarthritis (joint cartilage loss in spine): 13 people, 39.39%
Drug Ineffective: 11 people, 33.33%
Urinary Tract Infection: 11 people, 33.33%
Musculoskeletal Pain (pain affects the bones, muscles, ligaments, tendons, and nerves): 11 people, 33.33%
Sinusitis (inflammation of sinus): 10 people, 30.30%
Pain In Jaw: 10 people, 30.30%
Osteonecrosis Of Jaw (death of bone of jaw): 10 people, 30.30%
Osteomyelitis (infection of bone): 10 people, 30.30%

What are the existing conditions these people have? *

Spinal Osteoarthritis (joint cartilage loss in spine): 9 people, 27.27%
Sleep Disorder: 9 people, 27.27%
Osteoporosis (bones weak and more likely to break): 9 people, 27.27%
Osteopenia (a condition where bone mineral density is lower than normal): 9 people, 27.27%
Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 9 people, 27.27%
Depression: 9 people, 27.27%
Back Pain: 4 people, 12.12%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 3 people, 9.09%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 3 people, 9.09%
Menopausal Symptoms: 3 people, 9.09%

* Approximation only. Some reports may have incomplete information.

Do you take Feldene and have Sciatica?

- Check whether Sciatica is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Feldene:

Feldene (3,913 reports)

Sciatica treatments and more:

Sciatica (28,509 reports)

Browse all side effects of Feldene:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Sciatica:

Sciatica (1,145 drugs)

Browse all the conditions that are associated with Sciatica:

Sciatica (1,431 conditions)

Related publications that referenced our studies

Kola E, Bakalli I, Celaj E, Lluka R, Heta S, Sallabanda S, "Stomach perforation from piroxicam poisoning", Paediatrics Today, 2012 Jun .
Kola E, Bakalli I, Celaj E, Lluka R, Heta S, Sallabanda S, "Stomach perforation from piroxicam poisoning", Paediatrics Today, 2012 Jun .

How the study uses the data?

The study uses data from the FDA. It is based on piroxicam (the active ingredients of Feldene) and Feldene (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.