Femara and Eye swelling - a phase IV clinical study of FDA data

Summary:

Eye swelling is reported as a side effect among people who take Femara (letrozole), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Kisqali, and have Insulin resistance.

The phase IV clinical study analyzes which people have Eye swelling when taking Femara. It is created by eHealthMe based on reports of 19,093 people who have side effects when taking Femara from the FDA, and is updated regularly.

What is Femara?

Femara has active ingredients of letrozole. It is often used in breast cancer. eHealthMe is studying from 19,630 Femara users. Check the latest studies of Femara.

What is Eye swelling?

Eye swelling is found to be associated with 1,347 drugs and 1,583 conditions by eHealthMe. Check the latest studies of Eye swelling.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 30, 2026

19,093 people reported to have side effects when taking Femara.
Among them, 62 people (0.32%) have Eye swelling.

Among these 62 people:

How long have people been on Femara when they have Eye swelling? *

What is the gender of people who have Eye swelling when taking Femara? *

female: 100 %
male: 0.0 %

What is the age of people who have Eye swelling when taking Femara? *

What are other drugs people take besides Femara? *

What are other side effects people have besides Eye swelling? *

Headache (pain in head): 45 people, 72.58%
Pain: 41 people, 66.13%
Nausea (feeling of having an urge to vomit): 40 people, 64.52%
Eye Disorder: 40 people, 64.52%
Weight Increased: 40 people, 64.52%
Cough: 39 people, 62.90%
Malaise (a feeling of general discomfort or uneasiness): 38 people, 61.29%
Dizziness: 38 people, 61.29%
Dry Skin: 37 people, 59.68%
Back Pain: 37 people, 59.68%

What are the existing conditions these people have? *

Insulin Resistance: 22 people, 35.48%
Diabetes: 21 people, 33.87%
High Blood Cholesterol: 15 people, 24.19%
Gastritis (inflammation of stomach): 11 people, 17.74%
Breast Cancer Metastatic: 10 people, 16.13%
Metastases To Bone (cancer spreads to bone): 4 people, 6.45%
Depression: 3 people, 4.84%
Pain: 3 people, 4.84%
High Blood Pressure: 2 people, 3.23%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 3.23%

* Approximation only. Some reports may have incomplete information.

Do you take Femara and have Eye swelling?

- Check whether Eye swelling is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Femara:

Femara (19,630 reports)

Eye swelling treatments and more:

Eye swelling (38,718 reports)

Browse all side effects of Femara:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Eye swelling:

Eye swelling (1,347 drugs)

Browse all the conditions that are associated with Eye swelling:

Eye swelling (1,583 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on letrozole (the active ingredients of Femara) and Femara (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.