Fentanyl-100 and Application site bleeding - a phase IV clinical study of FDA data

Summary:

Application site bleeding is reported as a side effect among people who take Fentanyl-100 (fentanyl), especially for people who are male, 40-49 old, have been taking the drug for 1 - 2 years also take Duragesic-100, and have High blood pressure.

The phase IV clinical study analyzes which people have Application site bleeding when taking Fentanyl-100. It is created by eHealthMe based on reports of 6,924 people who have side effects when taking Fentanyl-100 from the FDA, and is updated regularly.

What is Fentanyl-100?

Fentanyl-100 has active ingredients of fentanyl. It is often used in pain. eHealthMe is studying from 7,047 Fentanyl-100 users. Check the latest studies of Fentanyl-100.

What is Application site bleeding?

Application site bleeding is found to be associated with 23 drugs and 164 conditions by eHealthMe. Check the latest studies of Application site bleeding.

On Jul, 15, 2026

6,924 people reported to have side effects when taking Fentanyl-100.
Among them, 12 people (0.17%) have Application site bleeding.

Could Fentanyl-100 cause Application site bleeding?

Among these 12 people:

How long have people been on Fentanyl-100 when they have Application site bleeding? *

What is the gender of people who have Application site bleeding when taking Fentanyl-100? *

female: 50 %
male: 50 %

What is the age of people who have Application site bleeding when taking Fentanyl-100? *

What are other drugs people take besides Fentanyl-100? *

What are other side effects people have besides Application site bleeding? *

Application Site Rash: 4 people, 33.33%
Application Site Reaction: 3 people, 25.00%
Application Site Vesicles (small bubble within a cell at application site): 3 people, 25.00%
Application Site Erythema (redness of the skin at application site): 3 people, 25.00%
Application Site Pain: 2 people, 16.67%
Drug Administration Error: 2 people, 16.67%
Drug Ineffective: 2 people, 16.67%
Application Site Urticaria: 2 people, 16.67%
Gastroenteritis Viral (inflammation of stomach and intestine caused by virus infection): 2 people, 16.67%
Application Site Haematoma (collection of blood outside the blood vessels at application site): 1 person, 8.33%

What are the existing conditions these people have? *

High Blood Pressure: 4 people, 33.33%
Systemic Lupus Erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue): 2 people, 16.67%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 2 people, 16.67%
Thyroid Diseases: 1 person, 8.33%
Swelling: 1 person, 8.33%
Pain In Extremity: 1 person, 8.33%
Neuralgia (pain in one or more nerves): 1 person, 8.33%
Headache (pain in head): 1 person, 8.33%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 8.33%
Fibromyalgia (a long-term condition which causes pain all over the body): 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

Do you take Fentanyl-100 and have Application site bleeding?

- Check whether Application site bleeding is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Fentanyl-100:

Fentanyl-100 (7,047 reports)

Browse all side effects of Fentanyl-100:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Application site bleeding:

Application site bleeding (23 drugs)

Browse all the conditions that are associated with Application site bleeding:

Application site bleeding (164 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on fentanyl (the active ingredients of Fentanyl-100) and Fentanyl-100 (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.