Fentanyl citrate and Angioedema - a phase IV clinical study of FDA data

Summary:

Angioedema is reported as a side effect among people who take Fentanyl citrate (fentanyl citrate), especially for people who are female, 60+ old, also take Ondansetron, and have Anaesthesia.

The phase IV clinical study analyzes which people have Angioedema when taking Fentanyl citrate. It is created by eHealthMe based on reports of 21,231 people who have side effects when taking Fentanyl citrate from the FDA, and is updated regularly.

What is Fentanyl citrate?

Fentanyl citrate has active ingredients of fentanyl citrate. It is often used in pain. eHealthMe is studying from 21,294 Fentanyl citrate users. Check the latest studies of Fentanyl citrate.

What is Angioedema?

Angioedema (rapid swelling of the dermis) is found to be associated with 1,199 drugs and 2,101 conditions by eHealthMe. Check the latest studies of Angioedema.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 03, 2026

21,231 people reported to have side effects when taking Fentanyl citrate.
Among them, 21 people (0.1%) have Angioedema.

Could Fentanyl citrate cause Angioedema?

Among these 21 people:

What is the gender of people who have Angioedema when taking Fentanyl citrate? *

female: 66.67 %
male: 33.33 %

What is the age of people who have Angioedema when taking Fentanyl citrate? *

What are other drugs people take besides Fentanyl citrate? *

What are other side effects people have besides Angioedema? *

Hypotension (abnormally low blood pressure): 4 people, 19.05%
Bronchospasm (spasm of bronchial smooth muscle producing narrowing of the bronchi): 4 people, 19.05%
Urticaria (rash of round, red welts on the skin that itch intensely): 4 people, 19.05%
Tryptase Increased: 4 people, 19.05%
Anaphylaxis (serious allergic reaction that is rapid in onset and may cause death): 4 people, 19.05%
Oropharyngeal Blistering (blister of oropharynx): 3 people, 14.29%
Face Oedema (swelling of face): 3 people, 14.29%
Procedural Hypotension: 3 people, 14.29%
Generalised Oedema (swelling all over the body): 3 people, 14.29%
Skin Blushing/flushing (a sudden reddening of the face, neck): 3 people, 14.29%

What are the existing conditions these people have? *

Anaesthesia: 2 people, 9.52%
Sedation: 1 person, 4.76%
Postpartum Sepsis (infection woman after childbirth): 1 person, 4.76%
Postpartum Haemorrhage (bleeding in woman after she has given birth): 1 person, 4.76%
Cancer Pain: 1 person, 4.76%

* Approximation only. Some reports may have incomplete information.

Do you take Fentanyl citrate and have Angioedema?

- Check whether Angioedema is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Fentanyl citrate:

Fentanyl citrate (21,294 reports)

Angioedema treatments and more:

Angioedema (44,989 reports)

Browse all side effects of Fentanyl citrate:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Angioedema:

Angioedema (1,199 drugs)

Browse all the conditions that are associated with Angioedema:

Angioedema (2,101 conditions)

Related publications that referenced our studies

Banaga, Y., Mohmmed, K., Mustafa, H., & Barrett, J, "Angioedema 2 months after Administration of Rivaroxaban (Xarelto)", J Clin Case Rep, 2014 Jan .
Banaga, Y., Mohmmed, K., Mustafa, H., & Barrett, J, "Angioedema 2 months after Administration of Rivaroxaban (Xarelto)", J Clin Case Rep, 2014 Jan .

How the study uses the data?

The study uses data from the FDA. It is based on fentanyl citrate (the active ingredients of Fentanyl citrate) and Fentanyl citrate (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.