Fentanyl citrate and Hyperbilirubinaemia - a phase IV clinical study of FDA data

Summary:

Hyperbilirubinaemia is reported as a side effect among people who take Fentanyl citrate (fentanyl citrate), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Methylprednisolone, and have Non-hodgkin's lymphoma.

The phase IV clinical study analyzes which people have Hyperbilirubinaemia when taking Fentanyl citrate. It is created by eHealthMe based on reports of 21,231 people who have side effects when taking Fentanyl citrate from the FDA, and is updated regularly.

What is Fentanyl citrate?

Fentanyl citrate has active ingredients of fentanyl citrate. It is often used in pain. eHealthMe is studying from 21,294 Fentanyl citrate users. Check the latest studies of Fentanyl citrate.

What is Hyperbilirubinaemia?

Hyperbilirubinaemia (excess of bilirubin in the blood) is found to be associated with 901 drugs and 1,074 conditions by eHealthMe. Check the latest studies of Hyperbilirubinaemia.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Sep, 01, 2026

21,231 people reported to have side effects when taking Fentanyl citrate.
Among them, 25 people (0.12%) have Hyperbilirubinaemia.

Could Fentanyl citrate cause Hyperbilirubinaemia?

Among these 25 people:

How long have people been on Fentanyl citrate when they have Hyperbilirubinaemia? *

  • < 1 month: 100 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Hyperbilirubinaemia when taking Fentanyl citrate? *

  • female: 48 %
  • male: 52 %

What is the age of people who have Hyperbilirubinaemia when taking Fentanyl citrate? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 4 %
  • 20-29: 8 %
  • 30-39: 20 %
  • 40-49: 0.0 %
  • 50-59: 12 %
  • 60+: 56 %

What are other drugs people take besides Fentanyl citrate? *

  1. Methylprednisolone: 11 people, 44.00%
  2. Vancomycin: 9 people, 36.00%
  3. Bactrim: 8 people, 32.00%
  4. Acyclovir: 7 people, 28.00%
  5. Meropenem: 7 people, 28.00%
  6. Pantoprazole: 6 people, 24.00%
  7. Cyclosporine: 5 people, 20.00%
  8. Nifedipine: 5 people, 20.00%
  9. Clofarabine: 5 people, 20.00%
  10. Mycophenolate Mofetil: 5 people, 20.00%

What are other side effects people have besides Hyperbilirubinaemia? *

  1. Arrhythmias (irregular heartbeat): 6 people, 24.00%
  2. Hypotension (abnormally low blood pressure): 6 people, 24.00%
  3. Thrombocytopenia (decrease of platelets in blood): 5 people, 20.00%
  4. Fluid Overload (too much fluid in the blood): 5 people, 20.00%
  5. Hyponatremia (abnormally low level of sodium in the blood; associated with dehydration): 5 people, 20.00%
  6. Cough: 4 people, 16.00%
  7. Blood Bilirubin Increased: 4 people, 16.00%
  8. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 4 people, 16.00%
  9. Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection): 4 people, 16.00%
  10. Nausea (feeling of having an urge to vomit): 4 people, 16.00%

What are the existing conditions these people have? *

  1. Non-Hodgkin's Lymphoma (malignant (cancer) cells form in the lymph system): 5 people, 20.00%
  2. Nausea (feeling of having an urge to vomit): 4 people, 16.00%
  3. Bone Marrow Conditioning Regimen: 4 people, 16.00%
  4. Breast Cancer: 3 people, 12.00%
  5. Breast Cancer Female: 3 people, 12.00%
  6. Acute Lymphocytic Leukemia (All) (cancer of the white blood cells characterized by excess lymphoblasts): 2 people, 8.00%
  7. Hiv Infection: 2 people, 8.00%
  8. Breast Cancer Stage Iv: 2 people, 8.00%
  9. Candidiasis (candidiasis or thrush is a fungal infection): 2 people, 8.00%
  10. Tooth Disorder (tooth disease): 1 person, 4.00%

* Approximation only. Some reports may have incomplete information.

Do you take Fentanyl citrate and have Hyperbilirubinaemia?

- Check whether Hyperbilirubinaemia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Fentanyl citrate:

Hyperbilirubinaemia treatments and more:

How severe was Hyperbilirubinaemia and when was it recovered:

Expand to all the drugs that have ingredients of fentanyl citrate:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Fentanyl citrate:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hyperbilirubinaemia:

Browse all the conditions that are associated with Hyperbilirubinaemia:


How the study uses the data?

The study uses data from the FDA. It is based on fentanyl citrate (the active ingredients of Fentanyl citrate) and Fentanyl citrate (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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