Fentanyl citrate and Splenomegaly - a phase IV clinical study of FDA data

Summary:

Splenomegaly is reported as a side effect among people who take Fentanyl citrate (fentanyl citrate), especially for people who are male, 30-39 old, have been taking the drug for < 1 month also take Furosemide, and have Histiocytosis haematophagic.

The phase IV clinical study analyzes which people have Splenomegaly when taking Fentanyl citrate. It is created by eHealthMe based on reports of 21,231 people who have side effects when taking Fentanyl citrate from the FDA, and is updated regularly.

What is Fentanyl citrate?

Fentanyl citrate has active ingredients of fentanyl citrate. It is often used in pain. eHealthMe is studying from 21,294 Fentanyl citrate users. Check the latest studies of Fentanyl citrate.

What is Splenomegaly?

Splenomegaly (enlargement of spleen) is found to be associated with 1,104 drugs and 1,478 conditions by eHealthMe. Check the latest studies of Splenomegaly.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 28, 2026

21,231 people reported to have side effects when taking Fentanyl citrate.
Among them, 22 people (0.1%) have Splenomegaly.

Could Fentanyl citrate cause Splenomegaly?

Among these 22 people:

How long have people been on Fentanyl citrate when they have Splenomegaly? *

What is the gender of people who have Splenomegaly when taking Fentanyl citrate? *

female: 31.82 %
male: 68.18 %

What is the age of people who have Splenomegaly when taking Fentanyl citrate? *

What are other drugs people take besides Fentanyl citrate? *

What are other side effects people have besides Splenomegaly? *

Fever: 8 people, 36.36%
Thrombocytopenia (decrease of platelets in blood): 8 people, 36.36%
Diarrhea: 7 people, 31.82%
Appetite - Decreased (decreased appetite occurs when you have a reduced desire to eat): 7 people, 31.82%
Atelectasis (partial or complete collapse of the lung): 7 people, 31.82%
Gastroenteritis (inflammation of stomach and intestine): 7 people, 31.82%
Fatigue (feeling of tiredness): 7 people, 31.82%
Stress And Anxiety: 7 people, 31.82%
Hepatomegaly (abnormal enlargement of the liver): 6 people, 27.27%
Hepatic Steatosis (fatty liver disease): 6 people, 27.27%

What are the existing conditions these people have? *

Juvenile Arthritis (arthritis-related condition that develops in children or teenagers): 4 people, 18.18%
Histiocytosis Haematophagic: 4 people, 18.18%
Multiple Myeloma (cancer of the plasma cells): 2 people, 9.09%
Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 2 people, 9.09%
Cough: 2 people, 9.09%
Anaesthesia: 2 people, 9.09%
Sinusitis (inflammation of sinus): 1 person, 4.55%
Respiratory Tract Infection: 1 person, 4.55%
Neck Pain: 1 person, 4.55%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 1 person, 4.55%

* Approximation only. Some reports may have incomplete information.

Do you take Fentanyl citrate and have Splenomegaly?

- Check whether Splenomegaly is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Fentanyl citrate:

Fentanyl citrate (21,294 reports)

Splenomegaly treatments and more:

Splenomegaly (17,257 reports)

Browse all side effects of Fentanyl citrate:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Splenomegaly:

Splenomegaly (1,104 drugs)

Browse all the conditions that are associated with Splenomegaly:

Splenomegaly (1,478 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on fentanyl citrate (the active ingredients of Fentanyl citrate) and Fentanyl citrate (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.