Fentanyl and Hypophosphataemia - a phase IV clinical study of FDA data

Summary:

Hypophosphataemia is reported as a side effect among people who take Fentanyl (fentanyl citrate), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Zometa, and have Multiple myeloma.

The phase IV clinical study analyzes which people have Hypophosphataemia when taking Fentanyl. It is created by eHealthMe based on reports of 72,646 people who have side effects when taking Fentanyl from the FDA, and is updated regularly.

What is Fentanyl?

Fentanyl has active ingredients of fentanyl citrate. It is often used in pain. eHealthMe is studying from 73,301 Fentanyl users. Check the latest studies of Fentanyl.

What is Hypophosphataemia?

Hypophosphataemia (electrolyte disturbance in which there is an abnormally low level of phosphate in the blood) is found to be associated with 873 drugs and 781 conditions by eHealthMe. Check the latest studies of Hypophosphataemia.

On Jul, 13, 2026

72,646 people reported to have side effects when taking Fentanyl.
Among them, 65 people (0.09%) have Hypophosphataemia.

Among these 65 people:

How long have people been on Fentanyl when they have Hypophosphataemia? *

What is the gender of people who have Hypophosphataemia when taking Fentanyl? *

female: 52.31 %
male: 47.69 %

What is the age of people who have Hypophosphataemia when taking Fentanyl? *

What are other drugs people take besides Fentanyl? *

What are other side effects people have besides Hypophosphataemia? *

Hypokalemia (low potassium): 28 people, 43.08%
Stress And Anxiety: 26 people, 40.00%
Anaemia (lack of blood): 25 people, 38.46%
Nausea And Vomiting: 24 people, 36.92%
Diarrhea: 24 people, 36.92%
Pleural Effusion (water on the lungs): 23 people, 35.38%
Osteonecrosis Of Jaw (death of bone of jaw): 23 people, 35.38%
Nausea (feeling of having an urge to vomit): 23 people, 35.38%
Rashes (redness): 23 people, 35.38%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 21 people, 32.31%

What are the existing conditions these people have? *

Multiple Myeloma (cancer of the plasma cells): 12 people, 18.46%
Osteoporosis (bones weak and more likely to break): 8 people, 12.31%
Deep Venous Thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis): 5 people, 7.69%
Metastases To Bone (cancer spreads to bone): 4 people, 6.15%
Cancer Pain: 3 people, 4.62%
Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 3 people, 4.62%
Avian Influenza (bird flu): 2 people, 3.08%
Hypotension (abnormally low blood pressure): 2 people, 3.08%
Wound: 2 people, 3.08%
Renal Cell Carcinoma Stage Iv (stage iv renal cell cancer have cancer that has spread to other organs, such as the lungs, liver, bones, or brain, and may have spread to lymph nodes): 2 people, 3.08%

* Approximation only. Some reports may have incomplete information.

Do you take Fentanyl and have Hypophosphataemia?

- Check whether Hypophosphataemia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Fentanyl:

Fentanyl (73,301 reports)

Browse all side effects of Fentanyl:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hypophosphataemia:

Hypophosphataemia (873 drugs)

Browse all the conditions that are associated with Hypophosphataemia:

Hypophosphataemia (781 conditions)

Related publications that referenced our studies

Mariappan R, Prasad A, Venkatraghavan L, "An uncommon cause for severe hypophosphataemia after transsphenoidal pituitary surgery", Journal of Neuroanaesthesiology and Critical Care, 2014 May .
Mariappan R, Prasad A, Venkatraghavan L, "An uncommon cause for severe hypophosphataemia after transsphenoidal pituitary surgery", Journal of Neuroanaesthesiology and Critical Care, 2014 May .

How the study uses the data?

The study uses data from the FDA. It is based on fentanyl citrate (the active ingredients of Fentanyl) and Fentanyl (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.