Fentanyl and Ischaemic stroke - a phase IV clinical study of FDA data

Summary:

Ischaemic stroke is reported as a side effect among people who take Fentanyl (fentanyl citrate), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Acetaminophen, and have High blood pressure.

The phase IV clinical study analyzes which people have Ischaemic stroke when taking Fentanyl. It is created by eHealthMe based on reports of 72,646 people who have side effects when taking Fentanyl from the FDA, and is updated regularly.

What is Fentanyl?

Fentanyl has active ingredients of fentanyl citrate. It is often used in pain. eHealthMe is studying from 73,301 Fentanyl users. Check the latest studies of Fentanyl.

What is Ischaemic stroke?

Ischaemic stroke (stroke; caused by an interruption in the flow of blood to the brain) is found to be associated with 848 drugs and 1,095 conditions by eHealthMe. Check the latest studies of Ischaemic stroke.

On Aug, 05, 2026

72,646 people reported to have side effects when taking Fentanyl.
Among them, 49 people (0.07%) have Ischaemic stroke.

Among these 49 people:

How long have people been on Fentanyl when they have Ischaemic stroke? *

What is the gender of people who have Ischaemic stroke when taking Fentanyl? *

female: 42.86 %
male: 57.14 %

What is the age of people who have Ischaemic stroke when taking Fentanyl? *

What are other drugs people take besides Fentanyl? *

What are other side effects people have besides Ischaemic stroke? *

Thrombocytopenia (decrease of platelets in blood): 5 people, 10.20%
Brain Oedema (excess accumulation of fluid in the intracellular or extracellular spaces of the brain): 5 people, 10.20%
Fatigue (feeling of tiredness): 4 people, 8.16%
Speech Impairment (Adult) (inability to speak (adult)): 4 people, 8.16%
Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 4 people, 8.16%
General Physical Health Deterioration (weak health status): 4 people, 8.16%
Unresponsive To Stimuli: 4 people, 8.16%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 4 people, 8.16%
Anaemia (lack of blood): 4 people, 8.16%
Transient Ischaemic Attack (a transient episode of neurologic dysfunction caused by ischemia (loss of blood flow)): 3 people, 6.12%

What are the existing conditions these people have? *

High Blood Pressure: 6 people, 12.24%
Cerebral Haemorrhage (bleeding within the brain): 4 people, 8.16%
Leiomyosarcoma Metastatic (a very rare soft tissue sarcoma (cancer) that grows in muscle tissue spreading to other parts): 4 people, 8.16%
Lung Cancer - Non-Small Cell (lung cancer): 3 people, 6.12%
Transient Ischaemic Attack (a transient episode of neurologic dysfunction caused by ischemia (loss of blood flow)): 3 people, 6.12%
Coronary Heart Disease (narrowing or blockage of the coronary arteries): 3 people, 6.12%
Sedation: 3 people, 6.12%
Depression: 3 people, 6.12%
High Blood Cholesterol: 3 people, 6.12%
Hypotension (abnormally low blood pressure): 3 people, 6.12%

* Approximation only. Some reports may have incomplete information.

Do you take Fentanyl and have Ischaemic stroke?

- Check whether Ischaemic stroke is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Fentanyl:

Fentanyl (73,301 reports)

Ischaemic stroke treatments and more:

Ischaemic stroke (25,786 reports)

Browse all side effects of Fentanyl:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Ischaemic stroke:

Ischaemic stroke (848 drugs)

Browse all the conditions that are associated with Ischaemic stroke:

Ischaemic stroke (1,095 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on fentanyl citrate (the active ingredients of Fentanyl) and Fentanyl (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.