Fetzima and Constipation - a phase IV clinical study of FDA data

Summary:

Constipation is reported as a side effect among people who take Fetzima (levomilnacipran hydrochloride), especially for people who are female, 50-59 old, have been taking the drug for < 1 month also take Synthroid, and have Stress and anxiety.

The phase IV clinical study analyzes which people have Constipation when taking Fetzima. It is created by eHealthMe based on reports of 2,014 people who have side effects when taking Fetzima from the FDA, and is updated regularly.

What is Fetzima?

Fetzima has active ingredients of levomilnacipran hydrochloride. It is often used in depression. eHealthMe is studying from 2,077 Fetzima users. Check the latest studies of Fetzima.

What is Constipation?

Constipation is found to be associated with 3,003 drugs and 4,577 conditions by eHealthMe. Check the latest studies of Constipation.

On Dec, 29, 2025

2,014 people reported to have side effects when taking Fetzima.
Among them, 47 people (2.33%) have Constipation.

Among these 47 people:

How long have people been on Fetzima when they have Constipation? *

What is the gender of people who have Constipation when taking Fetzima? *

female: 68.29 %
male: 31.71 %

What is the age of people who have Constipation when taking Fetzima? *

What are other drugs people take besides Fetzima? *

Synthroid: 8 people, 17.02%
Carafate: 4 people, 8.51%
Lisinopril And Hydrochlorothiazide: 4 people, 8.51%
Jakafi: 4 people, 8.51%
Singulair: 4 people, 8.51%
Vitamin D: 4 people, 8.51%
Vitamin D2: 3 people, 6.38%
Contrave: 3 people, 6.38%
Ondansetron: 3 people, 6.38%
Fish Oil: 3 people, 6.38%

What are other side effects people have besides Constipation? *

Fatigue (feeling of tiredness): 14 people, 29.79%
Nausea (feeling of having an urge to vomit): 12 people, 25.53%
Diarrhea: 8 people, 17.02%
Stress And Anxiety: 8 people, 17.02%
Nausea And Vomiting: 8 people, 17.02%
Headache (pain in head): 8 people, 17.02%
Hyperhidrosis (abnormally increased sweating): 8 people, 17.02%
Dizziness: 6 people, 12.77%
Drowsiness: 6 people, 12.77%
Drug Ineffective: 6 people, 12.77%

What are the existing conditions these people have? *

Stress And Anxiety: 5 people, 10.64%
Weight Loss: 4 people, 8.51%
Sleep Disorder: 4 people, 8.51%
Polycythaemia Vera (blood disorder in which the bone marrow makes too many red blood cells): 4 people, 8.51%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 3 people, 6.38%
Major Depression (a mood state that goes well beyond temporarily feeling sad or blue. it is a serious medical illness that affects one's thoughts, feelings): 3 people, 6.38%
Bronchiectasis (abnormal widening of the bronchi or their branches, causing a risk of infection): 2 people, 4.26%
Fibromyalgia (a long-term condition which causes pain all over the body): 2 people, 4.26%
Migraine (headache): 1 person, 2.13%
Chronic Myeloid Leukaemia (long lasting type of cancer that starts in the blood-forming cells of the bone marrow and invades the blood): 1 person, 2.13%

* Approximation only. Some reports may have incomplete information.

Do you take Fetzima and have Constipation?

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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Fetzima:

Fetzima (2,077 reports)

Constipation treatments and more:

Constipation (337,856 reports)

Browse all side effects of Fetzima:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Constipation:

Constipation (3,003 drugs)

Browse all the conditions that are associated with Constipation:

Constipation (4,577 conditions)

Drugs similar to Fetzima and Constipation :

How the study uses the data?

The study uses data from the FDA. It is based on levomilnacipran hydrochloride (the active ingredients of Fetzima) and Fetzima (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.