Fexofenadine hydrochloride and Hyperkalemia - a phase IV clinical study of FDA data

Summary:

Hyperkalemia is reported as a side effect among people who take Fexofenadine hydrochloride (fexofenadine hydrochloride), especially for people who are male, 60+ old, have been taking the drug for 1 - 6 months also take Furosemide, and have High blood pressure.

The phase IV clinical study analyzes which people have Hyperkalemia when taking Fexofenadine hydrochloride. It is created by eHealthMe based on reports of 6,114 people who have side effects when taking Fexofenadine hydrochloride from the FDA, and is updated regularly.

What is Fexofenadine hydrochloride?

Fexofenadine hydrochloride has active ingredients of fexofenadine hydrochloride. It is often used in allergies. eHealthMe is studying from 6,908 Fexofenadine hydrochloride users. Check the latest studies of Fexofenadine hydrochloride.

What is Hyperkalemia?

Hyperkalemia (damage to or disease of the kidney) is found to be associated with 1,951 drugs and 2,941 conditions by eHealthMe. Check the latest studies of Hyperkalemia.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 01, 2026

6,114 people reported to have side effects when taking Fexofenadine hydrochloride.
Among them, 33 people (0.54%) have Hyperkalemia.

Could Fexofenadine hydrochloride cause Hyperkalemia?

Among these 33 people:

How long have people been on Fexofenadine hydrochloride when they have Hyperkalemia? *

What is the gender of people who have Hyperkalemia when taking Fexofenadine hydrochloride? *

female: 43.75 %
male: 56.25 %

What is the age of people who have Hyperkalemia when taking Fexofenadine hydrochloride? *

What are other drugs people take besides Fexofenadine hydrochloride? *

Furosemide: 9 people, 27.27%
Magnesium Oxide: 8 people, 24.24%
Eliquis: 7 people, 21.21%
Aspirin: 5 people, 15.15%
Paclitaxel: 4 people, 12.12%
Carboplatin: 4 people, 12.12%
Spironolactone: 4 people, 12.12%
Zolpidem Tartrate: 3 people, 9.09%
Ketoprofen: 3 people, 9.09%
Moxifloxacin Hydrochloride: 3 people, 9.09%

What are other side effects people have besides Hyperkalemia? *

Oedema (fluid collection in tissue): 8 people, 24.24%
Renal Impairment (severely reduced kidney function): 8 people, 24.24%
Anaemia (lack of blood): 6 people, 18.18%
Gastrointestinal Haemorrhage (bleeding gastrointestinal tract): 6 people, 18.18%
Acute Kidney Failure: 5 people, 15.15%
Neuropathy Peripheral (surface nerve damage): 5 people, 15.15%
Chest Pain: 5 people, 15.15%
White Blood Cell Count Decreased: 4 people, 12.12%
Hypotension (abnormally low blood pressure): 4 people, 12.12%
Neutrophil Count Decreased (less than normal number of neutrophil a type of blood cell): 4 people, 12.12%

What are the existing conditions these people have? *

High Blood Pressure: 9 people, 27.27%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 7 people, 21.21%
Insomnia (sleeplessness): 7 people, 21.21%
Constipation: 6 people, 18.18%
Dyslipidaemia (abnormal amount of lipids): 6 people, 18.18%
Asteatosis (any disease that persistently causes the skin to dry): 5 people, 15.15%
Asthma: 5 people, 15.15%
Lung Cancer - Non-Small Cell (lung cancer): 4 people, 12.12%
Oedema (fluid collection in tissue): 4 people, 12.12%
Xeroderma (dry skin include itching and red, cracked or flaky skin): 3 people, 9.09%

* Approximation only. Some reports may have incomplete information.

Do you take Fexofenadine hydrochloride and have Hyperkalemia?

- Check whether Hyperkalemia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Fexofenadine hydrochloride:

Fexofenadine hydrochloride (6,908 reports)

Hyperkalemia treatments and more:

Hyperkalemia (78,085 reports)

Browse all side effects of Fexofenadine hydrochloride:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hyperkalemia:

Hyperkalemia (1,951 drugs)

Browse all the conditions that are associated with Hyperkalemia:

Hyperkalemia (2,941 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on fexofenadine hydrochloride (the active ingredients of Fexofenadine hydrochloride) and Fexofenadine hydrochloride (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.