Finasteride and Hyperkeratosis - a phase IV clinical study of FDA data

Summary:

Hyperkeratosis is reported as a side effect among people who take Finasteride (finasteride), especially for people who are male, 60+ old, have been taking the drug for 2 - 5 years also take Ramipril, and have Renal cell carcinoma.

The phase IV clinical study analyzes which people have Hyperkeratosis when taking Finasteride. It is created by eHealthMe based on reports of 42,469 people who have side effects when taking Finasteride from the FDA, and is updated regularly.

What is Finasteride?

Finasteride has active ingredients of finasteride. It is often used in prostate examination abnormal. eHealthMe is studying from 44,177 Finasteride users. Check the latest studies of Finasteride.

What is Hyperkeratosis?

Hyperkeratosis (thickening of the outer layer of the skin) is found to be associated with 778 drugs and 774 conditions by eHealthMe. Check the latest studies of Hyperkeratosis.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 20, 2026

42,469 people reported to have side effects when taking Finasteride.
Among them, 18 people (0.04%) have Hyperkeratosis.

Among these 18 people:

How long have people been on Finasteride when they have Hyperkeratosis? *

What is the gender of people who have Hyperkeratosis when taking Finasteride? *

female: 0.0 %
male: 100 %

What is the age of people who have Hyperkeratosis when taking Finasteride? *

What are other drugs people take besides Finasteride? *

What are other side effects people have besides Hyperkeratosis? *

Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure): 5 people, 27.78%
Weight Decreased: 5 people, 27.78%
Lung Infection: 4 people, 22.22%
Dyspnea (difficult or laboured breathing): 4 people, 22.22%
Fatigue (feeling of tiredness): 4 people, 22.22%
Skin Ulcer: 4 people, 22.22%
Lichen Planus (an inflammatory skin condition, characterized by an itchy, non-infectious rash): 4 people, 22.22%
Pneumonia: 4 people, 22.22%
Immunodeficiency: 4 people, 22.22%
Appetite - Decreased (decreased appetite occurs when you have a reduced desire to eat): 4 people, 22.22%

What are the existing conditions these people have? *

Renal Cell Carcinoma (a kidney cancer): 7 people, 38.89%
Thyroid Diseases: 2 people, 11.11%
Thyroid Cancer: 2 people, 11.11%
Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 2 people, 11.11%
Neuropathy Peripheral (surface nerve damage): 1 person, 5.56%
Metastatic Malignant Melanoma (spreadable cancer tumour of melanine): 1 person, 5.56%
High Density Lipoprotein Decreased: 1 person, 5.56%
Hepatic Neoplasm Malignant (liver cancer): 1 person, 5.56%
Heart Attack: 1 person, 5.56%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 5.56%

* Approximation only. Some reports may have incomplete information.

Do you take Finasteride and have Hyperkeratosis?

- Check whether Hyperkeratosis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Finasteride:

Finasteride (44,177 reports)

Hyperkeratosis treatments and more:

Hyperkeratosis (8,056 reports)

Browse all side effects of Finasteride:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hyperkeratosis:

Hyperkeratosis (778 drugs)

Browse all the conditions that are associated with Hyperkeratosis:

Hyperkeratosis (774 conditions)

Related publications that referenced our studies

Fouda AM, Bazeed AM, "Hematuria and Hematospermia Associated with the Use of Finasteride for the Treatment of Androgenic Alopecia: A Case Report", Drug Safety-Case Reports, 2017 Dec .
Fouda AM, Bazeed AM, "Hematuria and Hematospermia Associated with the Use of Finasteride for the Treatment of Androgenic Alopecia: A Case Report", Drug Safety-Case Reports, 2017 Dec .

How the study uses the data?

The study uses data from the FDA. It is based on finasteride (the active ingredients of Finasteride) and Finasteride (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.