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Fingolimod and Cryptococcosis - a phase IV clinical study of FDA data

Summary:

Cryptococcosis is reported as a side effect among people who take Fingolimod (fingolimod), especially for people who are female, 40-49 old, have been taking the drug for 10+ years also take Dexamethasone, and have Multiple sclerosis.

The phase IV clinical study analyzes which people have Cryptococcosis when taking Fingolimod. It is created by eHealthMe based on reports of 5,142 people who have side effects when taking Fingolimod from the FDA, and is updated regularly.

What is Fingolimod?

Fingolimod has active ingredients of fingolimod. eHealthMe is studying from 5,150 Fingolimod users. Check the latest studies of Fingolimod.

What is Cryptococcosis?

Cryptococcosis (potentially fatal fungal disease) is found to be associated with 147 drugs and 222 conditions by eHealthMe. Check the latest studies of Cryptococcosis.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 31, 2026

5,142 people reported to have side effects when taking Fingolimod.
Among them, 28 people (0.54%) have Cryptococcosis.

Could Fingolimod cause Cryptococcosis?

Among these 28 people:

How long have people been on Fingolimod when they have Cryptococcosis? *

  • < 1 month: 0.0 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 100 %

What is the gender of people who have Cryptococcosis when taking Fingolimod? *

  • female: 51.85 %
  • male: 48.15 %

What is the age of people who have Cryptococcosis when taking Fingolimod? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 69.23 %
  • 50-59: 15.38 %
  • 60+: 15.38 %

What are other drugs people take besides Fingolimod? *

  1. Fluconazole: 4 people, 14.29%
  2. Dexamethasone: 4 people, 14.29%
  3. Methylprednisolone: 2 people, 7.14%
  4. Flucytosine: 2 people, 7.14%
  5. Amphotericin B: 2 people, 7.14%
  6. Amantadine: 2 people, 7.14%
  7. Dexamethasone Sodium Phosphate: 1 person, 3.57%

What are other side effects people have besides Cryptococcosis? *

  1. Lymphopenia (an abnormally low level of lymphocytes in the blood): 10 people, 35.71%
  2. Chest Wall Mass: 9 people, 32.14%
  3. Osteomyelitis (infection of bone): 9 people, 32.14%
  4. Pathological Fracture (broken bone caused by disease): 6 people, 21.43%
  5. Encephalitis (inflammation of the brain): 5 people, 17.86%
  6. Brain Herniation (brain herniation is a potentially deadly side effect of very high intracranial pressure that occurs when a part of the brain is squeezed across structures within the skull): 4 people, 14.29%
  7. Itching: 4 people, 14.29%
  8. Ischaemic Stroke (stroke; caused by an interruption in the flow of blood to the brain): 3 people, 10.71%
  9. Cerebellar Ischaemia (lack of blood supply to cerebeller): 3 people, 10.71%
  10. Chest Pain: 3 people, 10.71%

What are the existing conditions these people have? *

  1. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 16 people, 57.14%
  2. Relapsing-Remitting Multiple Sclerosis (reoccurrence of an inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 11 people, 39.29%
  3. Chest Wall Mass: 4 people, 14.29%
  4. Multiple Sclerosis Relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 2 people, 7.14%
  5. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 1 person, 3.57%
  6. Pneumonia: 1 person, 3.57%
  7. Movement - Uncontrolled Or Slow: 1 person, 3.57%

* Approximation only. Some reports may have incomplete information.

Do you take Fingolimod and have Cryptococcosis?

- Check whether Cryptococcosis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Fingolimod:

Cryptococcosis treatments and more:

How severe was Cryptococcosis and when was it recovered:

Expand to all the drugs that have ingredients of fingolimod:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Fingolimod:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Cryptococcosis:

Browse all the conditions that are associated with Cryptococcosis:

Related publications that referenced our studies

How the study uses the data?

The study uses data from the FDA. It is based on fingolimod (the active ingredients of Fingolimod) and Fingolimod (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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