Fioricet w/ codeine and Nausea aggravated - a phase IV clinical study of FDA data

Summary:

Nausea aggravated is reported as a side effect among people who take Fioricet w/ codeine (acetaminophen; butalbital; caffeine; codeine phosphate), especially for people who are female, 40-49 old, also take Percocet, and have Hypothyroidism.

The phase IV clinical study analyzes which people have Nausea aggravated when taking Fioricet w/ codeine. It is created by eHealthMe based on reports of 123 people who have side effects when taking Fioricet w/ codeine from the FDA, and is updated regularly.

What is Fioricet w/ codeine?

Fioricet w/ codeine has active ingredients of acetaminophen; butalbital; caffeine; codeine phosphate. It is often used in migraine. eHealthMe is studying from 194 Fioricet w/ codeine users. Check the latest studies of Fioricet w/ codeine.

What is Nausea aggravated?

Nausea aggravated (an urge to vomit) is found to be associated with 3,410 drugs and 1,083 conditions by eHealthMe. Check the latest studies of Nausea aggravated.

On Jul, 28, 2026

123 people reported to have side effects when taking Fioricet w/ codeine.
Among them, 17 people (13.82%) have Nausea aggravated.

Could Fioricet w/ codeine cause Nausea aggravated?

Among these 17 people:

What is the gender of people who have Nausea aggravated when taking Fioricet w/ codeine? *

female: 76.47 %
male: 23.53 %

What is the age of people who have Nausea aggravated when taking Fioricet w/ codeine? *

What are other drugs people take besides Fioricet w/ codeine? *

What are other side effects people have besides Nausea aggravated? *

Bone Pain: 7 people, 41.18%
Dizziness: 7 people, 41.18%
Weight Decreased: 6 people, 35.29%
Dyspnea (difficult or laboured breathing): 6 people, 35.29%
Joint Pain: 6 people, 35.29%
Nausea And Vomiting: 6 people, 35.29%
Pain: 5 people, 29.41%
Fall: 5 people, 29.41%
Influenza Like Illness: 5 people, 29.41%
Abdominal Pain: 5 people, 29.41%

What are the existing conditions these people have? *

Depression: 3 people, 17.65%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 17.65%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 3 people, 17.65%
Indigestion: 2 people, 11.76%
Menopause (end of monthly cycles in women): 2 people, 11.76%
Asthma: 2 people, 11.76%
Birth Control: 2 people, 11.76%
Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures): 2 people, 11.76%
Idiopathic Thrombocytopenic Purpura (bleeding disorder in which the immune system destroys platelets, which are necessary for normal blood clotting): 2 people, 11.76%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 2 people, 11.76%

* Approximation only. Some reports may have incomplete information.

Do you take Fioricet w/ codeine and have Nausea aggravated?

- Check whether Nausea aggravated is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Fioricet w/ codeine:

Fioricet w/ codeine (194 reports)

Nausea aggravated treatments and more:

Nausea aggravated (214 reports)

How severe was Nausea aggravated and when was it recovered:

Nausea aggravated in Fioricet w/ codeine

Expand to all the drugs that have ingredients of acetaminophen; butalbital; caffeine; codeine phosphate:

Nausea aggravated and drugs with ingredients of acetaminophen; butalbital; caffeine; codeine phosphate

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Fioricet w/ codeine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Nausea aggravated:

Nausea aggravated (3,410 drugs)

Browse all the conditions that are associated with Nausea aggravated:

Nausea aggravated (1,083 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on acetaminophen; butalbital; caffeine; codeine phosphate (the active ingredients of Fioricet w/ codeine) and Fioricet w/ codeine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.