Fiorinal and Neck pain - a phase IV clinical study of FDA data

Summary:

Neck pain is reported as a side effect among people who take Fiorinal (aspirin; butalbital; caffeine), especially for people who are female, 60+ old, also take Imitrex, and have Immunodeficiency common variable.

The phase IV clinical study analyzes which people have Neck pain when taking Fiorinal. It is created by eHealthMe based on reports of 2,551 people who have side effects when taking Fiorinal from the FDA, and is updated regularly.

What is Fiorinal?

Fiorinal has active ingredients of aspirin; butalbital; caffeine. It is often used in migraine. eHealthMe is studying from 2,714 Fiorinal users. Check the latest studies of Fiorinal.

What is Neck pain?

Neck pain is found to be associated with 2,078 drugs and 2,817 conditions by eHealthMe. Check the latest studies of Neck pain.

On Jul, 15, 2026

2,551 people reported to have side effects when taking Fiorinal.
Among them, 43 people (1.69%) have Neck pain.

Among these 43 people:

What is the gender of people who have Neck pain when taking Fiorinal? *

female: 90.24 %
male: 9.76 %

What is the age of people who have Neck pain when taking Fiorinal? *

What are other drugs people take besides Fiorinal? *

What are other side effects people have besides Neck pain? *

Back Pain: 18 people, 41.86%
Fatigue (feeling of tiredness): 16 people, 37.21%
Nausea (feeling of having an urge to vomit): 13 people, 30.23%
Weakness: 12 people, 27.91%
Joint Pain: 11 people, 25.58%
Drug Ineffective: 11 people, 25.58%
Muscle Spasms (muscle contraction): 11 people, 25.58%
Vision Blurred: 9 people, 20.93%
Fibromyalgia (a long-term condition which causes pain all over the body): 9 people, 20.93%
Insomnia (sleeplessness): 8 people, 18.60%

What are the existing conditions these people have? *

Pain: 4 people, 9.30%
Osteoporosis (bones weak and more likely to break): 4 people, 9.30%
Immunodeficiency Common Variable: 4 people, 9.30%
Skin Wrinkling (wrinkle on skin): 3 people, 6.98%
Seizures (abnormal excessive or synchronous neuronal activity in the brain): 3 people, 6.98%
Back Pain: 3 people, 6.98%
Primary Immunodeficiency Syndrome: 3 people, 6.98%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 3 people, 6.98%
Stress And Anxiety: 2 people, 4.65%
Mental Disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability): 2 people, 4.65%

* Approximation only. Some reports may have incomplete information.

Do you take Fiorinal and have Neck pain?

- Check whether Neck pain is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Fiorinal:

Fiorinal (2,714 reports)

Neck pain treatments and more:

Neck pain (83,324 reports)

Browse all side effects of Fiorinal:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Neck pain:

Neck pain (2,078 drugs)

Browse all the conditions that are associated with Neck pain:

Neck pain (2,817 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on aspirin; butalbital; caffeine (the active ingredients of Fiorinal) and Fiorinal (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.