Fish oil and Extremity necrosis - a phase IV clinical study of FDA data

Summary:

Extremity necrosis is reported as a side effect among people who take Fish oil (fish oil), especially for people who are female, 50-59 old, also take Zopiclone, and have Rheumatoid arthritis.

The phase IV clinical study analyzes which people have Extremity necrosis when taking Fish oil. It is created by eHealthMe based on reports of 109,866 people who have side effects when taking Fish oil from the FDA, and is updated regularly.

What is Fish oil?

Fish oil has active ingredients of fish oil. It is often used in high blood cholesterol. eHealthMe is studying from 112,933 Fish oil users. Check the latest studies of Fish oil.

What is Extremity necrosis?

Extremity necrosis (death of body tissue of arms and legs) is found to be associated with 301 drugs and 409 conditions by eHealthMe. Check the latest studies of Extremity necrosis.

On Jul, 12, 2026

109,866 people reported to have side effects when taking Fish oil.
Among them, 12 people (0.01%) have Extremity necrosis.

Could Fish oil cause Extremity necrosis?

Among these 12 people:

What is the gender of people who have Extremity necrosis when taking Fish oil? *

female: 81.82 %
male: 18.18 %

What is the age of people who have Extremity necrosis when taking Fish oil? *

What are other drugs people take besides Fish oil? *

What are other side effects people have besides Extremity necrosis? *

Stress And Anxiety: 7 people, 58.33%
Insomnia (sleeplessness): 7 people, 58.33%
Bile Acid Malabsorption: 7 people, 58.33%
Poor Peripheral Circulation: 7 people, 58.33%
Foot Deformity (functional disability of foot): 7 people, 58.33%
Oropharyngeal Pain: 7 people, 58.33%
Ear Pain: 7 people, 58.33%
Joint Injury: 6 people, 50.00%
Road Traffic Accident: 6 people, 50.00%
Headache (pain in head): 6 people, 50.00%

What are the existing conditions these people have? *

Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 9 people, 75.00%
Muscle Spasms (muscle contraction): 7 people, 58.33%
Pain: 6 people, 50.00%
Type 2 Diabetes: 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

Do you take Fish oil and have Extremity necrosis?

- Check whether Extremity necrosis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Fish oil:

Fish oil (112,933 reports)

Browse all side effects of Fish oil:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Extremity necrosis:

Extremity necrosis (301 drugs)

Browse all the conditions that are associated with Extremity necrosis:

Extremity necrosis (409 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on fish oil (the active ingredients of Fish oil) and Fish oil (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.