Fish oil and Hepatotoxicity - a phase IV clinical study of FDA data

Summary:

Hepatotoxicity is reported as a side effect among people who take Fish oil (fish oil), especially for people who are female, 50-59 old, have been taking the drug for 1 - 6 months also take Lorazepam, and have Dyslipidaemia.

The phase IV clinical study analyzes which people have Hepatotoxicity when taking Fish oil. It is created by eHealthMe based on reports of 109,866 people who have side effects when taking Fish oil from the FDA, and is updated regularly.

What is Fish oil?

Fish oil has active ingredients of fish oil. It is often used in high blood cholesterol. eHealthMe is studying from 112,933 Fish oil users. Check the latest studies of Fish oil.

What is Hepatotoxicity?

Hepatotoxicity (chemical-driven liver damage) is found to be associated with 1,087 drugs and 1,249 conditions by eHealthMe. Check the latest studies of Hepatotoxicity.

On Jul, 15, 2026

109,866 people reported to have side effects when taking Fish oil.
Among them, 78 people (0.07%) have Hepatotoxicity.

Among these 78 people:

How long have people been on Fish oil when they have Hepatotoxicity? *

What is the gender of people who have Hepatotoxicity when taking Fish oil? *

female: 96 %
male: 4 %

What is the age of people who have Hepatotoxicity when taking Fish oil? *

What are other drugs people take besides Fish oil? *

Progesterone: 51 people, 65.38%
Lorazepam: 51 people, 65.38%
Lactobacillus Acidophilus: 47 people, 60.26%
Estradiol: 47 people, 60.26%
Ergocalciferol: 46 people, 58.97%
Ubidecarenone: 40 people, 51.28%
Vitamin C: 33 people, 42.31%
Thioctic Acid: 33 people, 42.31%
Varenicline: 31 people, 39.74%
Lactobacillus Rhamnosus: 28 people, 35.90%

What are other side effects people have besides Hepatotoxicity? *

Hepatic Necrosis (large portions of liver die off due to severe liver disease): 35 people, 44.87%
Hepatic Cirrhosis (chronic liver disease characterized by replacement of liver tissue by fibrosis, scar tissue): 34 people, 43.59%
Hepatic Encephalopathy (spectrum of neuropsychiatric abnormalities in patients with liver failure): 34 people, 43.59%
Drug-Induced Liver Injury (diseases of the liver that are caused by physician-prescribed medications): 34 people, 43.59%
Nausea (feeling of having an urge to vomit): 9 people, 11.54%
Fatigue (feeling of tiredness): 8 people, 10.26%
Nausea And Vomiting: 6 people, 7.69%
Rhabdomyolysis (a condition in which damaged skeletal muscle tissue breaks down): 4 people, 5.13%
Fever: 4 people, 5.13%
Hepatic Enzyme Increased: 4 people, 5.13%

What are the existing conditions these people have? *

Dyslipidaemia (abnormal amount of lipids): 5 people, 6.41%
Glucose Tolerance Impaired (blood glucose is raised beyond normal levels, but not high enough to warrant a diabetes diagnosis): 4 people, 5.13%
Pain: 4 people, 5.13%
High Blood Pressure: 3 people, 3.85%
Cardiac Disorder: 3 people, 3.85%
Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 2 people, 2.56%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 2 people, 2.56%
Multiple Myeloma (cancer of the plasma cells): 2 people, 2.56%
Arthropathy: 2 people, 2.56%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 2 people, 2.56%

* Approximation only. Some reports may have incomplete information.

Do you take Fish oil and have Hepatotoxicity?

- Check whether Hepatotoxicity is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Fish oil:

Fish oil (112,933 reports)

Hepatotoxicity treatments and more:

Hepatotoxicity (23,823 reports)

Browse all side effects of Fish oil:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hepatotoxicity:

Hepatotoxicity (1,087 drugs)

Browse all the conditions that are associated with Hepatotoxicity:

Hepatotoxicity (1,249 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on fish oil (the active ingredients of Fish oil) and Fish oil (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.