Flavin and Constipation - a phase IV clinical study of FDA data

Summary:

Constipation is reported as a side effect among people who take Flavin (riboflavin (vitamin b2)), especially for people who are male, 60+ old, have been taking the drug for 10+ years also take Allopurinol, and have Bacterial infection.

The phase IV clinical study analyzes which people have Constipation when taking Flavin. It is created by eHealthMe based on reports of 2,778 people who have side effects when taking Flavin from the FDA, and is updated regularly.

What is Flavin?

Flavin has active ingredients of riboflavin (vitamin b2). eHealthMe is studying from 2,870 Flavin users. Check the latest studies of Flavin.

What is Constipation?

Constipation is found to be associated with 3,004 drugs and 4,606 conditions by eHealthMe. Check the latest studies of Constipation.



On Jun, 26, 2026

2,778 people reported to have side effects when taking Flavin.
Among them, 161 people (5.8%) have Constipation.

Could Flavin cause Constipation?

Among these 161 people:

How long have people been on Flavin when they have Constipation? *

  • < 1 month: 0.0 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 100 %

What is the gender of people who have Constipation when taking Flavin? *

  • female: 30.5 %
  • male: 69.5 %

What is the age of people who have Constipation when taking Flavin? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.79 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 8.73 %
  • 50-59: 6.35 %
  • 60+: 84.13 %

What are other drugs people take besides Flavin? *

  1. Allopurinol: 111 people, 68.94%
  2. Simvastatin: 110 people, 68.32%
  3. Acetaminophen: 109 people, 67.70%
  4. Ondansetron: 107 people, 66.46%
  5. Calcitriol: 106 people, 65.84%
  6. Metronidazole: 106 people, 65.84%
  7. Melatonin: 105 people, 65.22%
  8. Gabapentin: 104 people, 64.60%
  9. Phytonadione: 103 people, 63.98%
  10. Polyethylene Glycol 3350: 103 people, 63.98%

What are other side effects people have besides Constipation? *

  1. Nausea (feeling of having an urge to vomit): 124 people, 77.02%
  2. Abdominal Pain: 113 people, 70.19%
  3. Nausea And Vomiting: 112 people, 69.57%
  4. Abdominal Distension: 111 people, 68.94%
  5. Ascites (accumulation of fluid in the abdominal cavity): 107 people, 66.46%
  6. Stress And Anxiety: 103 people, 63.98%
  7. Appendicitis (inflammation of the appendix): 102 people, 63.35%
  8. Cardiogenic Shock (inadequate circulation of blood): 99 people, 61.49%
  9. Ventricular Fibrillation (abnormally irregular heart rhythm): 99 people, 61.49%
  10. Hyponatremia (abnormally low level of sodium in the blood; associated with dehydration): 99 people, 61.49%

What are the existing conditions these people have? *

  1. Anaemia (lack of blood): 107 people, 66.46%
  2. Cardiogenic Shock (inadequate circulation of blood): 107 people, 66.46%
  3. Bacterial Infection: 107 people, 66.46%
  4. Blood Uric Acid Increased: 106 people, 65.84%
  5. Stress And Anxiety: 105 people, 65.22%
  6. Diabetes: 104 people, 64.60%
  7. Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 104 people, 64.60%
  8. Iron Deficiency: 103 people, 63.98%
  9. Sleep Disorder: 103 people, 63.98%
  10. Dyspnea (difficult or laboured breathing): 103 people, 63.98%

* Approximation only. Some reports may have incomplete information.

Do you take Flavin and have Constipation?

- Check whether Constipation is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Flavin:

Constipation treatments and more:

How severe was Constipation and when was it recovered:

Expand to all the drugs that have ingredients of riboflavin (vitamin b2):

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Flavin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Constipation:

Browse all the conditions that are associated with Constipation:


How the study uses the data?

The study uses data from the FDA. It is based on riboflavin (vitamin b2) (the active ingredients of Flavin) and Flavin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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