Flecainide acetate and Angioedema - a phase IV clinical study of FDA data

Summary:

Angioedema is reported as a side effect among people who take Flecainide acetate (flecainide acetate), especially for people who are female, 60+ old, also take Omeprazole, and have Indigestion.

The phase IV clinical study analyzes which people have Angioedema when taking Flecainide acetate. It is created by eHealthMe based on reports of 6,177 people who have side effects when taking Flecainide acetate from the FDA, and is updated regularly.

What is Flecainide acetate?

Flecainide acetate has active ingredients of flecainide acetate. It is often used in atrial fibrillation/flutter. eHealthMe is studying from 7,176 Flecainide acetate users. Check the latest studies of Flecainide acetate.

What is Angioedema?

Angioedema (rapid swelling of the dermis) is found to be associated with 1,199 drugs and 2,101 conditions by eHealthMe. Check the latest studies of Angioedema.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 03, 2026

6,177 people reported to have side effects when taking Flecainide acetate.
Among them, 15 people (0.24%) have Angioedema.

Could Flecainide acetate cause Angioedema?

Among these 15 people:

What is the gender of people who have Angioedema when taking Flecainide acetate? *

female: 80 %
male: 20 %

What is the age of people who have Angioedema when taking Flecainide acetate? *

What are other drugs people take besides Flecainide acetate? *

Zopiclone: 6 people, 40.00%
Omeprazole: 6 people, 40.00%
Citalopram Hydrobromide: 5 people, 33.33%
Nulytely: 4 people, 26.67%
Amoxicillin: 2 people, 13.33%
Albuterol: 1 person, 6.67%
Amaryl: 1 person, 6.67%
Aspirin: 1 person, 6.67%
Atacand: 1 person, 6.67%
Calciparine: 1 person, 6.67%

What are other side effects people have besides Angioedema? *

Dyspnea (difficult or laboured breathing): 4 people, 26.67%
Pharyngeal Oedema (abnormal accumulation of fluid in the cavities and intercellular spaces of the pharyngeal): 2 people, 13.33%
Respiratory Disorder (respiratory disease): 2 people, 13.33%
Hypersensitivity: 2 people, 13.33%
Swallowing Difficulty: 2 people, 13.33%
Cardio-Respiratory Arrest (sudden dysfunction of heart and lungs): 1 person, 6.67%
Central Venous Pressure Increased: 1 person, 6.67%
Drug Intolerance (drug sensitivity): 1 person, 6.67%
Cardiac Failure: 1 person, 6.67%
Localised Oedema (fluid retention in a particular part of the body): 1 person, 6.67%

What are the existing conditions these people have? *

Stress And Anxiety: 6 people, 40.00%
Indigestion: 6 people, 40.00%
High Blood Pressure: 5 people, 33.33%
Constipation: 4 people, 26.67%
Respiratory Tract Infection: 1 person, 6.67%
Pain: 1 person, 6.67%
Multiple Myeloma (cancer of the plasma cells): 1 person, 6.67%
Ill-Defined Disorder: 1 person, 6.67%
Helicobacter Infection (helicobacter pylori (h. pylori) infects stomach): 1 person, 6.67%
Haemorrhage (bleeding): 1 person, 6.67%

* Approximation only. Some reports may have incomplete information.

Do you take Flecainide acetate and have Angioedema?

- Check whether Angioedema is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Flecainide acetate:

Flecainide acetate (7,176 reports)

Angioedema treatments and more:

Angioedema (44,989 reports)

Browse all side effects of Flecainide acetate:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Angioedema:

Angioedema (1,199 drugs)

Browse all the conditions that are associated with Angioedema:

Angioedema (2,101 conditions)

Related publications that referenced our studies

Banaga, Y., Mohmmed, K., Mustafa, H., & Barrett, J, "Angioedema 2 months after Administration of Rivaroxaban (Xarelto)", J Clin Case Rep, 2014 Jan .
Banaga, Y., Mohmmed, K., Mustafa, H., & Barrett, J, "Angioedema 2 months after Administration of Rivaroxaban (Xarelto)", J Clin Case Rep, 2014 Jan .

How the study uses the data?

The study uses data from the FDA. It is based on flecainide acetate (the active ingredients of Flecainide acetate) and Flecainide acetate (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.