Flector and Sciatica - a phase IV clinical study of FDA data

Summary:

Sciatica is reported as a side effect among people who take Flector (diclofenac epolamine), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Ambien, and have Back disorder.

The phase IV clinical study analyzes which people have Sciatica when taking Flector. It is created by eHealthMe based on reports of 5,075 people who have side effects when taking Flector from the FDA, and is updated regularly.

What is Flector?

Flector has active ingredients of diclofenac epolamine. It is often used in pain. eHealthMe is studying from 5,112 Flector users. Check the latest studies of Flector.

What is Sciatica?

Sciatica (a set of symptoms including pain caused by general compression or irritation of one of five spinal nerve roots of each sciatic nerve) is found to be associated with 1,145 drugs and 1,422 conditions by eHealthMe. Check the latest studies of Sciatica.



On Nov, 17, 2025

5,075 people reported to have side effects when taking Flector.
Among them, 11 people (0.22%) have Sciatica.

Could Flector cause Sciatica?

Among these 11 people:

How long have people been on Flector when they have Sciatica? *

  • < 1 month: 50 %
  • 1 - 6 months: 50 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Sciatica when taking Flector? *

  • female: 80 %
  • male: 20 %

What is the age of people who have Sciatica when taking Flector? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 10 %
  • 40-49: 10 %
  • 50-59: 30 %
  • 60+: 50 %

What are other drugs people take besides Flector? *

  1. Allopurinol: 3 people, 27.27%
  2. Zometa: 3 people, 27.27%
  3. Flexeril: 3 people, 27.27%
  4. Zofran: 3 people, 27.27%
  5. Lasix: 3 people, 27.27%
  6. Zanaflex: 3 people, 27.27%
  7. Omeprazole: 3 people, 27.27%
  8. Ambien: 3 people, 27.27%
  9. Motrin: 2 people, 18.18%
  10. Lyrica: 2 people, 18.18%

What are other side effects people have besides Sciatica? *

  1. Joint Pain: 5 people, 45.45%
  2. Stress And Anxiety: 5 people, 45.45%
  3. Pain In Extremity: 4 people, 36.36%
  4. Fever: 3 people, 27.27%
  5. Intervertebral Disc Degeneration (spinal disc degeneration): 3 people, 27.27%
  6. Pneumonia: 3 people, 27.27%
  7. Muscle Aches (muscle pain): 3 people, 27.27%
  8. Cervical Spinal Stenosis (narrowing of the spinal canal in the neck): 3 people, 27.27%
  9. Herpes Zoster: 2 people, 18.18%
  10. Gastrointestinal Tract Irritation: 2 people, 18.18%

What are the existing conditions these people have? *

  1. Back Disorder: 3 people, 27.27%
  2. Arthritis (form of joint disorder that involves inflammation of one or more joints): 2 people, 18.18%
  3. Musculoskeletal Pain (pain affects the bones, muscles, ligaments, tendons, and nerves): 2 people, 18.18%
  4. Muscle Aches (muscle pain): 2 people, 18.18%
  5. Bursitis (inflammation of a bursa, typically one in the knee, elbow, or shoulder): 2 people, 18.18%
  6. Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 2 people, 18.18%
  7. Fistula (an abnormal connection or passageway between two): 2 people, 18.18%
  8. Diabetes: 1 person, 9.09%
  9. Bone Disorder: 1 person, 9.09%
  10. Breast Cancer: 1 person, 9.09%

* Approximation only. Some reports may have incomplete information.

Do you take Flector and have Sciatica?

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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Flector:

Sciatica treatments and more:

How severe was Sciatica and when was it recovered:

Expand to all the drugs that have ingredients of diclofenac epolamine:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Flector:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Sciatica:

Browse all the conditions that are associated with Sciatica:

Drugs similar to Flector and Sciatica :


How the study uses the data?

The study uses data from the FDA. It is based on diclofenac epolamine (the active ingredients of Flector) and Flector (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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