Flolan and Pain in extremity - a phase IV clinical study of FDA data

Summary:

Pain in extremity is reported as a side effect among people who take Flolan (epoprostenol sodium), especially for people who are female, 50-59 old, have been taking the drug for < 1 month also take Coumadin, and have Primary pulmonary hypertension.

The phase IV clinical study analyzes which people have Pain in extremity when taking Flolan. It is created by eHealthMe based on reports of 10,044 people who have side effects when taking Flolan from the FDA, and is updated regularly.

What is Flolan?

Flolan has active ingredients of epoprostenol sodium. eHealthMe is studying from 10,067 Flolan users. Check the latest studies of Flolan.

What is Pain in extremity?

Pain in extremity is found to be associated with 3,250 drugs and 4,288 conditions by eHealthMe. Check the latest studies of Pain in extremity.

On Jun, 11, 2026

10,044 people reported to have side effects when taking Flolan.
Among them, 384 people (3.82%) have Pain in extremity.

Among these 384 people:

* Approximation only. Some reports may have incomplete information.

Do you take Flolan and have Pain in extremity?

- Check whether Pain in extremity is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Flolan:

Flolan (10,067 reports)

Pain in extremity treatments and more:

Pain in extremity (376,792 reports)

How severe was Pain in extremity and when was it recovered:

Pain in extremity in Flolan

Expand to all the drugs that have ingredients of epoprostenol sodium:

Pain in extremity and drugs with ingredients of epoprostenol sodium (2,015 reports)

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Flolan:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Pain in extremity:

Pain in extremity (3,250 drugs)

Browse all the conditions that are associated with Pain in extremity:

Pain in extremity (4,288 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on epoprostenol sodium (the active ingredients of Flolan) and Flolan (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.