Flomax and Knee joint replacement - a phase IV clinical study of FDA data

Summary:

Knee joint replacement is reported as a side effect among people who take Flomax (tamsulosin hydrochloride), especially for people who are male, 60+ old, also take Aspirin, and have Rheumatoid arthritis.

The phase IV clinical study analyzes which people have Knee joint replacement when taking Flomax. It is created by eHealthMe based on reports of 50,469 people who have side effects when taking Flomax from the FDA, and is updated regularly.

What is Flomax?

Flomax has active ingredients of tamsulosin hydrochloride. It is often used in enlarged prostate. eHealthMe is studying from 52,865 Flomax users. Check the latest studies of Flomax.

What is Knee joint replacement?

Knee joint replacement is found to be associated with 954 drugs and 1,228 conditions by eHealthMe. Check the latest studies of Knee joint replacement.

On Apr, 30, 2026

50,469 people reported to have side effects when taking Flomax.
Among them, 72 people (0.14%) have Knee joint replacement.

Could Flomax cause Knee joint replacement?

Among these 72 people:

What is the gender of people who have Knee joint replacement when taking Flomax? *

female: 11.76 %
male: 88.24 %

What is the age of people who have Knee joint replacement when taking Flomax? *

What are other drugs people take besides Flomax? *

What are other side effects people have besides Knee joint replacement? *

Joint Pain: 11 people, 15.28%
Gait Disturbance: 10 people, 13.89%
Dizziness: 9 people, 12.50%
Osteoarthritis (a joint disease caused by cartilage loss in a joint): 9 people, 12.50%
Pain: 9 people, 12.50%
Sleep Apnea Syndrome: 9 people, 12.50%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 8 people, 11.11%
Fall: 8 people, 11.11%
Nausea (feeling of having an urge to vomit): 7 people, 9.72%
Memory Loss: 7 people, 9.72%

What are the existing conditions these people have? *

Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 12 people, 16.67%
High Blood Cholesterol: 11 people, 15.28%
Pain: 8 people, 11.11%
Depression: 8 people, 11.11%
High Blood Pressure: 7 people, 9.72%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 7 people, 9.72%
Psoriasis (immune-mediated disease that affects the skin): 7 people, 9.72%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 5 people, 6.94%
Hypersensitivity: 5 people, 6.94%
Stress And Anxiety: 5 people, 6.94%

* Approximation only. Some reports may have incomplete information.

Do you take Flomax and have Knee joint replacement?

- Check whether Knee joint replacement is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Flomax:

Flomax (52,865 reports)

Browse all side effects of Flomax:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Knee joint replacement:

Knee joint replacement (954 drugs)

Browse all the conditions that are associated with Knee joint replacement:

Knee joint replacement (1,228 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on tamsulosin hydrochloride (the active ingredients of Flomax) and Flomax (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.