Florinef and Disease recurrence - a phase IV clinical study of FDA data

Summary:

Disease recurrence is reported as a side effect among people who take Florinef (fludrocortisone acetate), especially for people who are male, 60+ old, have been taking the drug for 5 - 10 years also take Hydrocortisone, and have Depression.

The phase IV clinical study analyzes which people have Disease recurrence when taking Florinef. It is created by eHealthMe based on reports of 3,634 people who have side effects when taking Florinef from the FDA, and is updated regularly.

What is Florinef?

Florinef has active ingredients of fludrocortisone acetate. It is often used in addison's disease. eHealthMe is studying from 3,834 Florinef users. Check the latest studies of Florinef.

What is Disease recurrence?

Disease recurrence is found to be associated with 1,242 drugs and 1,551 conditions by eHealthMe. Check the latest studies of Disease recurrence.

On Jul, 17, 2026

3,634 people reported to have side effects when taking Florinef.
Among them, 13 people (0.36%) have Disease recurrence.

Could Florinef cause Disease recurrence?

Among these 13 people:

How long have people been on Florinef when they have Disease recurrence? *

What is the gender of people who have Disease recurrence when taking Florinef? *

female: 46.15 %
male: 53.85 %

What is the age of people who have Disease recurrence when taking Florinef? *

What are other drugs people take besides Florinef? *

What are other side effects people have besides Disease recurrence? *

Atelectasis (partial or complete collapse of the lung): 3 people, 23.08%
Dehydration (dryness resulting from the removal of water): 3 people, 23.08%
Weakness: 2 people, 15.38%
Growth Retardation (delayed growth): 2 people, 15.38%
Aggression: 2 people, 15.38%
Appetite - Increased (increased appetite is when you want to eat much more often or in larger quantities than your body requires): 2 people, 15.38%
Bone Development Abnormal: 2 people, 15.38%
Chest Pain: 2 people, 15.38%
Conductive Deafness (deafness due to a problem in conducting sound waves): 2 people, 15.38%
Dizziness: 2 people, 15.38%

What are the existing conditions these people have? *

Stress And Anxiety: 1 person, 7.69%
Pain: 1 person, 7.69%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 1 person, 7.69%
Metabolic Encephalopathy (disorder or disease of the brain due to the body's disability to use energy): 1 person, 7.69%
Indigestion: 1 person, 7.69%
Hepatic Encephalopathy (spectrum of neuropsychiatric abnormalities in patients with liver failure): 1 person, 7.69%
Hepatic Cirrhosis (chronic liver disease characterized by replacement of liver tissue by fibrosis, scar tissue): 1 person, 7.69%
Hallucination, Visual (seeing things that aren't there): 1 person, 7.69%
Diabetes: 1 person, 7.69%
Depression: 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

Do you take Florinef and have Disease recurrence?

- Check whether Disease recurrence is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Florinef:

Florinef (3,834 reports)

Browse all side effects of Florinef:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Disease recurrence:

Disease recurrence (1,242 drugs)

Browse all the conditions that are associated with Disease recurrence:

Disease recurrence (1,551 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on fludrocortisone acetate (the active ingredients of Florinef) and Florinef (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.