Floxin and Insomnia - a phase IV clinical study of FDA data

Summary:

Insomnia is reported as a side effect among people who take Floxin (ofloxacin), especially for people who are female, 40-49 old, have been taking the drug for < 1 month also take Neurontin, and have Urinary tract infection.

The phase IV clinical study analyzes which people have Insomnia when taking Floxin. It is created by eHealthMe based on reports of 1,723 people who have side effects when taking Floxin from the FDA, and is updated regularly.

What is Floxin?

Floxin has active ingredients of ofloxacin. eHealthMe is studying from 1,737 Floxin users. Check the latest studies of Floxin.

What is Insomnia?

Insomnia (sleeplessness) is found to be associated with 3,119 drugs and 5,159 conditions by eHealthMe. Check the latest studies of Insomnia.



On Apr, 06, 2026

1,723 people reported to have side effects when taking Floxin.
Among them, 36 people (2.09%) have Insomnia.

Could Floxin cause Insomnia?

Among these 36 people:

How long have people been on Floxin when they have Insomnia? *

  • < 1 month: 100 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Insomnia when taking Floxin? *

  • female: 79.41 %
  • male: 20.59 %

What is the age of people who have Insomnia when taking Floxin? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 4.17 %
  • 20-29: 0.0 %
  • 30-39: 33.33 %
  • 40-49: 45.83 %
  • 50-59: 4.17 %
  • 60+: 12.5 %

What are other drugs people take besides Floxin? *

  1. Neurontin: 8 people, 22.22%
  2. Ambien: 7 people, 19.44%
  3. Levaquin: 7 people, 19.44%
  4. Cipro: 6 people, 16.67%
  5. Flagyl: 5 people, 13.89%
  6. Toradol: 5 people, 13.89%
  7. Prednisone: 5 people, 13.89%
  8. Zoloft: 5 people, 13.89%
  9. Oxycodone: 4 people, 11.11%
  10. Klonopin: 4 people, 11.11%

What are other side effects people have besides Insomnia? *

  1. Weakness: 20 people, 55.56%
  2. Pain: 18 people, 50.00%
  3. Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect): 17 people, 47.22%
  4. Dizziness: 16 people, 44.44%
  5. Headache (pain in head): 15 people, 41.67%
  6. Depression: 14 people, 38.89%
  7. Stress And Anxiety: 14 people, 38.89%
  8. Dyspnea (difficult or laboured breathing): 14 people, 38.89%
  9. Tremor (trembling or shaking movements in one or more parts of your body): 14 people, 38.89%
  10. Tendonitis (a condition that causes pain and swelling of tendons): 13 people, 36.11%

What are the existing conditions these people have? *

  1. Urinary Tract Infection: 11 people, 30.56%
  2. Pain: 5 people, 13.89%
  3. Nausea (feeling of having an urge to vomit): 2 people, 5.56%
  4. Urticaria (rash of round, red welts on the skin that itch intensely): 1 person, 2.78%
  5. Infection: 1 person, 2.78%
  6. Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 1 person, 2.78%
  7. Back Pain: 1 person, 2.78%
  8. Birth Control: 1 person, 2.78%
  9. Bladder Cancer: 1 person, 2.78%
  10. Blood Potassium Decreased: 1 person, 2.78%

* Approximation only. Some reports may have incomplete information.

Do you take Floxin and have Insomnia?

- Check whether Insomnia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Floxin:

Insomnia treatments and more:

How severe was Insomnia and when was it recovered:

Expand to all the drugs that have ingredients of ofloxacin:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Floxin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Insomnia:

Browse all the conditions that are associated with Insomnia:


How the study uses the data?

The study uses data from the FDA. It is based on ofloxacin (the active ingredients of Floxin) and Floxin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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