Fluconazole and Fibrosis - a phase IV clinical study of FDA data

Summary:

Fibrosis is reported as a side effect among people who take Fluconazole (fluconazole), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Zometa, and have Gastroesophageal reflux disease.

The phase IV clinical study analyzes which people have Fibrosis when taking Fluconazole. It is created by eHealthMe based on reports of 69,269 people who have side effects when taking Fluconazole from the FDA, and is updated regularly.

What is Fluconazole?

Fluconazole has active ingredients of fluconazole. It is often used in vaginal yeast infection. eHealthMe is studying from 70,481 Fluconazole users. Check the latest studies of Fluconazole.

What is Fibrosis?

Fibrosis (formation of excess fibrous connective tissue in an organ or tissue) is found to be associated with 699 drugs and 681 conditions by eHealthMe. Check the latest studies of Fibrosis.



On Jul, 16, 2026

69,269 people reported to have side effects when taking Fluconazole.
Among them, 53 people (0.08%) have Fibrosis.

Could Fluconazole cause Fibrosis?

Among these 53 people:

How long have people been on Fluconazole when they have Fibrosis? *

  • < 1 month: 100 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Fibrosis when taking Fluconazole? *

  • female: 50.94 %
  • male: 49.06 %

What is the age of people who have Fibrosis when taking Fluconazole? *

  • 0-1: 0.0 %
  • 2-9: 2.56 %
  • 10-19: 5.13 %
  • 20-29: 2.56 %
  • 30-39: 5.13 %
  • 40-49: 15.38 %
  • 50-59: 33.33 %
  • 60+: 35.9 %

What are other drugs people take besides Fluconazole? *

  1. Zometa: 21 people, 39.62%
  2. Gabapentin: 20 people, 37.74%
  3. Protonix: 19 people, 35.85%
  4. Dexamethasone: 18 people, 33.96%
  5. Nasonex: 16 people, 30.19%
  6. Flonase: 16 people, 30.19%
  7. Allegra: 16 people, 30.19%
  8. Cytoxan: 15 people, 28.30%
  9. Lipitor: 15 people, 28.30%
  10. Thalidomide: 15 people, 28.30%

What are other side effects people have besides Fibrosis? *

  1. Hypoaesthesia (reduced sense of touch or sensation): 22 people, 41.51%
  2. Pain: 21 people, 39.62%
  3. Oedema Peripheral (superficial swelling): 20 people, 37.74%
  4. Osteomyelitis (infection of bone): 20 people, 37.74%
  5. Atelectasis (partial or complete collapse of the lung): 20 people, 37.74%
  6. Rashes (redness): 20 people, 37.74%
  7. Cough: 19 people, 35.85%
  8. Osteonecrosis Of Jaw (death of bone of jaw): 18 people, 33.96%
  9. Constipation: 18 people, 33.96%
  10. Intervertebral Disc Degeneration (spinal disc degeneration): 17 people, 32.08%

What are the existing conditions these people have? *

  1. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 10 people, 18.87%
  2. Pain: 9 people, 16.98%
  3. Respiratory Disorder (respiratory disease): 7 people, 13.21%
  4. Depression: 7 people, 13.21%
  5. Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 7 people, 13.21%
  6. Breast Cancer: 5 people, 9.43%
  7. Metastases To Bone (cancer spreads to bone): 5 people, 9.43%
  8. Bone Cancer Metastatic: 5 people, 9.43%
  9. Gastrointestinal Stoma Complication (complication of an opening surgically made in digestive tract): 4 people, 7.55%
  10. High Blood Pressure: 4 people, 7.55%

* Approximation only. Some reports may have incomplete information.

Do you take Fluconazole and have Fibrosis?

- Check whether Fibrosis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Fluconazole:

Fibrosis treatments and more:

How severe was Fibrosis and when was it recovered:

Expand to all the drugs that have ingredients of fluconazole:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Fluconazole:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Fibrosis:

Browse all the conditions that are associated with Fibrosis:


How the study uses the data?

The study uses data from the FDA. It is based on fluconazole (the active ingredients of Fluconazole) and Fluconazole (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



Recent studies on eHealthMe: