Fluconazole and Reflux oesophagitis - a phase IV clinical study of FDA data

Summary:

Reflux oesophagitis is reported as a side effect among people who take Fluconazole (fluconazole), especially for people who are male, 2-9 old, also take Allopurinol, and have Eczema.

The phase IV clinical study analyzes which people have Reflux oesophagitis when taking Fluconazole. It is created by eHealthMe based on reports of 69,269 people who have side effects when taking Fluconazole from the FDA, and is updated regularly.

What is Fluconazole?

Fluconazole has active ingredients of fluconazole. It is often used in vaginal yeast infection. eHealthMe is studying from 70,481 Fluconazole users. Check the latest studies of Fluconazole.

What is Reflux oesophagitis?

Reflux oesophagitis (an oesophageal mucosal injury that occurs of gastric contents into the oesophagus) is found to be associated with 339 drugs and 571 conditions by eHealthMe. Check the latest studies of Reflux oesophagitis.

On Jul, 17, 2026

69,269 people reported to have side effects when taking Fluconazole.
Among them, 27 people (0.04%) have Reflux oesophagitis.

Could Fluconazole cause Reflux oesophagitis?

Among these 27 people:

What is the gender of people who have Reflux oesophagitis when taking Fluconazole? *

female: 16.67 %
male: 83.33 %

What is the age of people who have Reflux oesophagitis when taking Fluconazole? *

What are other drugs people take besides Fluconazole? *

Allopurinol: 17 people, 62.96%
Cytoxan: 16 people, 59.26%
Vancomycin: 16 people, 59.26%
Neupogen: 15 people, 55.56%
Velcade: 13 people, 48.15%
Chlorhexidine Gluconate: 12 people, 44.44%
Peridex: 11 people, 40.74%
Cyclophosphamide: 10 people, 37.04%
Lorazepam: 10 people, 37.04%
Elidel: 9 people, 33.33%

What are other side effects people have besides Reflux oesophagitis? *

Stress And Anxiety: 16 people, 59.26%
Fever: 14 people, 51.85%
Cough: 14 people, 51.85%
Depression: 12 people, 44.44%
Diarrhea: 9 people, 33.33%
Pneumonia: 9 people, 33.33%
Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters): 8 people, 29.63%
Injury: 8 people, 29.63%
Upper Respiratory Tract Infection: 8 people, 29.63%
Haemorrhoids (a swollen vein or group of veins in the region of the anus): 8 people, 29.63%

What are the existing conditions these people have? *

Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters): 9 people, 33.33%
Neoplasm Malignant (cancer tumour): 8 people, 29.63%
Multiple Myeloma (cancer of the plasma cells): 5 people, 18.52%
Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 1 person, 3.70%
Peripheral Neuropathy (damage to nerves of the peripheral nervous system): 1 person, 3.70%
Nausea And Vomiting: 1 person, 3.70%
Mycobacterium Avium Complex Infection: 1 person, 3.70%
Insomnia (sleeplessness): 1 person, 3.70%
Hiv Infection: 1 person, 3.70%
Disseminated Cytomegaloviral Infection (group of herpes viruses infection): 1 person, 3.70%

* Approximation only. Some reports may have incomplete information.

Do you take Fluconazole and have Reflux oesophagitis?

- Check whether Reflux oesophagitis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Fluconazole:

Fluconazole (70,481 reports)

Browse all side effects of Fluconazole:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Reflux oesophagitis:

Reflux oesophagitis (339 drugs)

Browse all the conditions that are associated with Reflux oesophagitis:

Reflux oesophagitis (571 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on fluconazole (the active ingredients of Fluconazole) and Fluconazole (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.