Fludara and Bradycardia - a phase IV clinical study of FDA data

Summary:

Bradycardia is reported as a side effect among people who take Fludara (fludarabine phosphate), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Cyclophosphamide, and have Chronic lymphocytic leukaemia.

The phase IV clinical study analyzes which people have Bradycardia when taking Fludara. It is created by eHealthMe based on reports of 46,669 people who have side effects when taking Fludara from the FDA, and is updated regularly.

What is Fludara?

Fludara has active ingredients of fludarabine phosphate. eHealthMe is studying from 46,686 Fludara users. Check the latest studies of Fludara.

What is Bradycardia?

Bradycardia (abnormally slow heart action) is found to be associated with 1,926 drugs and 3,118 conditions by eHealthMe. Check the latest studies of Bradycardia.

On Jul, 06, 2026

46,669 people reported to have side effects when taking Fludara.
Among them, 74 people (0.16%) have Bradycardia.

Among these 74 people:

How long have people been on Fludara when they have Bradycardia? *

What is the gender of people who have Bradycardia when taking Fludara? *

female: 32.84 %
male: 67.16 %

What is the age of people who have Bradycardia when taking Fludara? *

What are other drugs people take besides Fludara? *

What are other side effects people have besides Bradycardia? *

Hypotension (abnormally low blood pressure): 32 people, 43.24%
Cytokine Release Syndrome (immediate complication occurring with the use of anti-t cell antibody infusions): 19 people, 25.68%
Fever: 18 people, 24.32%
Neurotoxicity (when the exposure to natural or artificial toxic substances, which are called neurotoxins, alters the normal activity of the nervous system): 18 people, 24.32%
Chest Pain: 17 people, 22.97%
Fatigue (feeling of tiredness): 15 people, 20.27%
Nausea (feeling of having an urge to vomit): 15 people, 20.27%
Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets): 10 people, 13.51%
Chills (felling of cold): 10 people, 13.51%
Dyspnea (difficult or laboured breathing): 9 people, 12.16%

What are the existing conditions these people have? *

Chronic Lymphocytic Leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 19 people, 25.68%
Non-Hodgkin's Lymphoma (malignant (cancer) cells form in the lymph system): 15 people, 20.27%
Bone Marrow Conditioning Regimen: 15 people, 20.27%
Nausea (feeling of having an urge to vomit): 6 people, 8.11%
B-Cell Small Lymphocytic Lymphoma (blood cancer affecting b cells): 6 people, 8.11%
Sleep Disorder: 5 people, 6.76%
Constipation: 5 people, 6.76%
Pain: 4 people, 5.41%
Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection): 3 people, 4.05%
Bone Marrow Failure: 3 people, 4.05%

* Approximation only. Some reports may have incomplete information.

Do you take Fludara and have Bradycardia?

- Check whether Bradycardia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Fludara:

Fludara (46,686 reports)

Bradycardia treatments and more:

Bradycardia (61,180 reports)

Browse all side effects of Fludara:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Bradycardia:

Bradycardia (1,926 drugs)

Browse all the conditions that are associated with Bradycardia:

Bradycardia (3,118 conditions)

Related publications that referenced our studies

Schlumbrecht MP, Hehr K, "Cisplatin-induced bradycardia and the importance of the QT interval", Journal of Oncology Pharmacy Practice, 2015 Jan .
Oflaz MB, Kucukdurmaz Z, Guven AS, Karapinar H, Kaya A, Sancakdar E, Deveci K, Gul I, Erdem A, Cevit O, Icagasioglu FD, "Bradycardia seen in children with Crimean-Congo hemorrhagic fever", Vector-Borne and Zoonotic Diseases, 2013 Nov .
Schlumbrecht MP, Hehr K, "Cisplatin-induced bradycardia and the importance of the QT interval", Journal of Oncology Pharmacy Practice, 2015 Jan .
Oflaz MB, Kucukdurmaz Z, Guven AS, Karapinar H, Kaya A, Sancakdar E, Deveci K, Gul I, Erdem A, Cevit O, Icagasioglu FD, "Bradycardia seen in children with Crimean-Congo hemorrhagic fever", Vector-Borne and Zoonotic Diseases, 2013 Nov .

How the study uses the data?

The study uses data from the FDA. It is based on fludarabine phosphate (the active ingredients of Fludara) and Fludara (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.