Fludara and C. diff - a phase IV clinical study of FDA data

Summary:

C. diff is reported as a side effect among people who take Fludara (fludarabine phosphate), especially for people who are male, 50-59 old, have been taking the drug for < 1 month also take Cyclophosphamide, and have Bone marrow conditioning regimen.

The phase IV clinical study analyzes which people have C. diff when taking Fludara. It is created by eHealthMe based on reports of 46,669 people who have side effects when taking Fludara from the FDA, and is updated regularly.

What is Fludara?

Fludara has active ingredients of fludarabine phosphate. eHealthMe is studying from 46,686 Fludara users. Check the latest studies of Fludara.

What is C. diff?

C. diff is found to be associated with 1,573 drugs and 1,776 conditions by eHealthMe. Check the latest studies of C. diff.

On Mar, 26, 2026

46,669 people reported to have side effects when taking Fludara.
Among them, 255 people (0.55%) have C. diff.

Among these 255 people:

How long have people been on Fludara when they have C. diff? *

What is the gender of people who have C. diff when taking Fludara? *

female: 49.33 %
male: 50.67 %

What is the age of people who have C. diff when taking Fludara? *

What are other drugs people take besides Fludara? *

Cyclophosphamide: 85 people, 33.33%
Cyclosporine: 42 people, 16.47%
Methotrexate: 35 people, 13.73%
Busulfan: 32 people, 12.55%
Tacrolimus: 29 people, 11.37%
Cytarabine: 29 people, 11.37%
Mycophenolate Mofetil: 28 people, 10.98%
Acyclovir: 23 people, 9.02%
Bendamustine: 22 people, 8.63%
Melphalan: 22 people, 8.63%

What are other side effects people have besides C. diff? *

Fever: 55 people, 21.57%
Thrombocytopenia (decrease of platelets in blood): 44 people, 17.25%
Febrile Neutropenia (fever with reduced white blood cells): 43 people, 16.86%
Cytokine Release Syndrome (immediate complication occurring with the use of anti-t cell antibody infusions): 37 people, 14.51%
Diarrhea: 34 people, 13.33%
Pneumonia: 26 people, 10.20%
High Blood Pressure: 22 people, 8.63%
Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection): 21 people, 8.24%
Mucosal Inflammation (infection of mucous membrane): 20 people, 7.84%
Blood Bilirubin Increased: 20 people, 7.84%

What are the existing conditions these people have? *

Bone Marrow Conditioning Regimen: 90 people, 35.29%
Non-Hodgkin's Lymphoma (malignant (cancer) cells form in the lymph system): 29 people, 11.37%
Chronic Lymphocytic Leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 24 people, 9.41%
Juvenile Rheumatoid Arthritis (joint inflammation in children due to systemic disease): 20 people, 7.84%
Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 20 people, 7.84%
Pancreatic Carcinoma Metastatic (pancreatic cancer- metastatic): 16 people, 6.27%
Acute Lymphocytic Leukemia (All) (cancer of the white blood cells characterized by excess lymphoblasts): 15 people, 5.88%
Graft Versus Host Disease (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body): 14 people, 5.49%
Multiple Myeloma (cancer of the plasma cells): 12 people, 4.71%
Fever: 12 people, 4.71%

* Approximation only. Some reports may have incomplete information.

Do you take Fludara and have C. diff?

- Check whether C. diff is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Fludara:

Fludara (46,686 reports)

C. diff treatments and more:

C. diff (13,845 reports)

Browse all side effects of Fludara:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with C. diff:

C. diff (1,573 drugs)

Browse all the conditions that are associated with C. diff:

C. diff (1,776 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on fludarabine phosphate (the active ingredients of Fludara) and Fludara (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.