Fludara and Poikiloderma - a phase IV clinical study of FDA data

Summary:

Poikiloderma is reported as a side effect among people who take Fludara (fludarabine phosphate), especially for people who are male, 50-59 old, also take Ciclosporin, and have Acute graft versus host disease.

The phase IV clinical study analyzes which people have Poikiloderma when taking Fludara. It is created by eHealthMe based on reports of 46,669 people who have side effects when taking Fludara from the FDA, and is updated regularly.

What is Fludara?

Fludara has active ingredients of fludarabine phosphate. eHealthMe is studying from 46,686 Fludara users. Check the latest studies of Fludara.

What is Poikiloderma?

Poikiloderma (pigmentary and atrophic changes in the skin) is found to be associated with 35 drugs and 42 conditions by eHealthMe. Check the latest studies of Poikiloderma.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 25, 2026

46,669 people reported to have side effects when taking Fludara.
Among them, 13 people (0.03%) have Poikiloderma.

Among these 13 people:

What is the gender of people who have Poikiloderma when taking Fludara? *

female: 0.0 %
male: 100 %

What is the age of people who have Poikiloderma when taking Fludara? *

What are other drugs people take besides Fludara? *

Magnesium: 5 people, 38.46%
Ciclosporin: 5 people, 38.46%
Folate: 4 people, 30.77%
Methotrexate: 3 people, 23.08%
Enalapril Maleate: 3 people, 23.08%
Cyclosporine: 3 people, 23.08%
Busulfan: 3 people, 23.08%
Bisoprolol Fumarate: 3 people, 23.08%
Acyclovir: 3 people, 23.08%
Sulfamethoxazole And Trimethoprim: 2 people, 15.38%

What are other side effects people have besides Poikiloderma? *

Renal Tubular Necrosis (death of kidney tubules): 12 people, 92.31%
Reticulocytosis (a condition where there is an increase in reticulocytes): 12 people, 92.31%
Meningioma (a diverse set of tumours arising from the meninges): 12 people, 92.31%
Cytomegalovirus Infection: 12 people, 92.31%
Lichenoid Keratosis (a skin disorder described by rapid growing, reddish to brown, benign (noncancerous) lesion on the skin): 12 people, 92.31%
Rash Maculo-Papular (red area on the skin that is covered with small confluent bumps): 12 people, 92.31%
Anaemia (lack of blood): 12 people, 92.31%
Nephrotic Syndrome (kidney disease with proteinuria, hypoalbuminemia, and oedema): 12 people, 92.31%
Skin Hypertrophy (skin cells enlarges): 12 people, 92.31%
Thrombocytopenia (decrease of platelets in blood): 12 people, 92.31%

What are the existing conditions these people have? *

Acute Graft Versus Host Disease (acute complication following an allogeneic tissue/blood transplant): 8 people, 61.54%
Graft Versus Host Disease (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body): 7 people, 53.85%
Bone Marrow Conditioning Regimen: 6 people, 46.15%
Glomerulonephritis Minimal Lesion (a disease of the kidney that causes nephrotic syndrome and usually affects children): 4 people, 30.77%
Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 4 people, 30.77%
Graft Versus Host Disease In Skin (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the skin): 1 person, 7.69%
Acute Graft Versus Host Disease In Skin (acute complication on skin following an allogeneic tissue/blood transplant): 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

Do you take Fludara and have Poikiloderma?

- Check whether Poikiloderma is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Fludara:

Fludara (46,686 reports)

Poikiloderma treatments and more:

Poikiloderma (128 reports)

Browse all side effects of Fludara:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Poikiloderma:

Poikiloderma (35 drugs)

Browse all the conditions that are associated with Poikiloderma:

Poikiloderma (42 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on fludarabine phosphate (the active ingredients of Fludara) and Fludara (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.