Fludarabine phosphate and Necrosis - a phase IV clinical study of FDA data

Summary:

Necrosis is reported as a side effect among people who take Fludarabine phosphate (fludarabine phosphate), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Cyclophosphamide, and have Chronic lymphocytic leukaemia.

The phase IV clinical study analyzes which people have Necrosis when taking Fludarabine phosphate. It is created by eHealthMe based on reports of 12,833 people who have side effects when taking Fludarabine phosphate from the FDA, and is updated regularly.

What is Fludarabine phosphate?

Fludarabine phosphate has active ingredients of fludarabine phosphate. eHealthMe is studying from 12,840 Fludarabine phosphate users. Check the latest studies of Fludarabine phosphate.

What is Necrosis?

Necrosis (the death of body tissue) is found to be associated with 751 drugs and 969 conditions by eHealthMe. Check the latest studies of Necrosis.

On Aug, 09, 2026

12,833 people reported to have side effects when taking Fludarabine phosphate.
Among them, 22 people (0.17%) have Necrosis.

Could Fludarabine phosphate cause Necrosis?

Among these 22 people:

How long have people been on Fludarabine phosphate when they have Necrosis? *

What is the gender of people who have Necrosis when taking Fludarabine phosphate? *

female: 54.55 %
male: 45.45 %

What is the age of people who have Necrosis when taking Fludarabine phosphate? *

What are other drugs people take besides Fludarabine phosphate? *

Cyclophosphamide: 8 people, 36.36%
Acetaminophen: 4 people, 18.18%
Cyclosporine: 4 people, 18.18%
Nystatin: 3 people, 13.64%
Dexamethasone: 3 people, 13.64%
Minipress: 3 people, 13.64%
Glucophage: 3 people, 13.64%
Atropine: 3 people, 13.64%
Tenormin: 3 people, 13.64%
Dexamethasone Sodium Phosphate: 2 people, 9.09%

What are other side effects people have besides Necrosis? *

Multi-Organ Failure (multisystem organ failure): 7 people, 31.82%
Fever: 6 people, 27.27%
Cardiac Arrest: 4 people, 18.18%
Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure): 4 people, 18.18%
Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection): 4 people, 18.18%
Lymph Follicular Hypertrophy (an increase in the size of the lymph node follicles): 4 people, 18.18%
Acute Kidney Failure: 4 people, 18.18%
Malignant Neoplasm Progression (cancer tumour came back): 3 people, 13.64%
Hepatomegaly (abnormal enlargement of the liver): 3 people, 13.64%
Rashes (redness): 3 people, 13.64%

What are the existing conditions these people have? *

Chronic Lymphocytic Leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 9 people, 40.91%
Venoocclusive Liver Disease (small veins in the liver are obstructed): 1 person, 4.55%
Non-Hodgkin's Lymphoma (malignant (cancer) cells form in the lymph system): 1 person, 4.55%
Graft Versus Host Disease (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body): 1 person, 4.55%
Burkitt Lymphoma (cancer of the lymphatic system): 1 person, 4.55%
Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 1 person, 4.55%

* Approximation only. Some reports may have incomplete information.

Do you take Fludarabine phosphate and have Necrosis?

- Check whether Necrosis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Fludarabine phosphate:

Fludarabine phosphate (12,840 reports)

Necrosis treatments and more:

Necrosis (8,274 reports)

Browse all side effects of Fludarabine phosphate:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Necrosis:

Necrosis (751 drugs)

Browse all the conditions that are associated with Necrosis:

Necrosis (969 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on fludarabine phosphate (the active ingredients of Fludarabine phosphate) and Fludarabine phosphate (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.