Fluoride and Eye pain - a phase IV clinical study of FDA data

Summary:

Eye pain is reported as a side effect among people who take Fluoride (fluoride), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Oxervate, and have Neurotrophic keratopathy.

The phase IV clinical study analyzes which people have Eye pain when taking Fluoride. It is created by eHealthMe based on reports of 2,283 people who have side effects when taking Fluoride from the FDA, and is updated regularly.

What is Fluoride?

Fluoride has active ingredients of fluoride. eHealthMe is studying from 2,301 Fluoride users. Check the latest studies of Fluoride.

What is Eye pain?

Eye pain is found to be associated with 1,759 drugs and 2,465 conditions by eHealthMe. Check the latest studies of Eye pain.



On Jul, 12, 2026

2,283 people reported to have side effects when taking Fluoride.
Among them, 14 people (0.61%) have Eye pain.

Could Fluoride cause Eye pain?

Among these 14 people:

How long have people been on Fluoride when they have Eye pain? *

  • < 1 month: 100 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Eye pain when taking Fluoride? *

  • female: 78.57 %
  • male: 21.43 %

What is the age of people who have Eye pain when taking Fluoride? *

  • 0-1: 0.0 %
  • 2-9: 12.5 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 25.0 %
  • 60+: 62.5 %

What are other drugs people take besides Fluoride? *

  1. Oxervate: 5 people, 35.71%
  2. Vitamin D3: 3 people, 21.43%
  3. Elavil: 2 people, 14.29%
  4. Prozac: 2 people, 14.29%
  5. Ibuprofen: 2 people, 14.29%
  6. Lisinopril: 2 people, 14.29%
  7. Lucentis: 2 people, 14.29%
  8. Macrodantin: 2 people, 14.29%
  9. Melatonin: 2 people, 14.29%
  10. Humalog: 2 people, 14.29%

What are other side effects people have besides Eye pain? *

  1. Visual Acuity Reduced (reduced clearness of vision): 6 people, 42.86%
  2. Eye Irritation: 6 people, 42.86%
  3. Ocular Hyperaemia (an abnormally large amount of blood in eye): 5 people, 35.71%
  4. Headache (pain in head): 4 people, 28.57%
  5. Vision Blurred: 4 people, 28.57%
  6. Injury Corneal: 4 people, 28.57%
  7. Eye Injury: 4 people, 28.57%
  8. Blindness: 4 people, 28.57%
  9. Corneal Infection (corneal infection): 4 people, 28.57%
  10. Corneal Scar (nullah): 4 people, 28.57%

What are the existing conditions these people have? *

  1. Neurotrophic Keratopathy (decreased corneal sensitivity and poor corneal healing): 5 people, 35.71%
  2. Sleep Disorder: 2 people, 14.29%
  3. Panic Disorder: 2 people, 14.29%
  4. Depression: 2 people, 14.29%
  5. Birth Control: 2 people, 14.29%
  6. Age-Related Macular Degeneration: 2 people, 14.29%
  7. Hypersensitivity: 1 person, 7.14%

* Approximation only. Some reports may have incomplete information.

Do you take Fluoride and have Eye pain?

- Check whether Eye pain is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Fluoride:

Eye pain treatments and more:

How severe was Eye pain and when was it recovered:

Expand to all the drugs that have ingredients of fluoride:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Fluoride:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Eye pain:

Browse all the conditions that are associated with Eye pain:


How the study uses the data?

The study uses data from the FDA. It is based on fluoride (the active ingredients of Fluoride) and Fluoride (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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