Fluorouracil and Bronchiectasis - a phase IV clinical study of FDA data

Summary:

Bronchiectasis is reported as a side effect among people who take Fluorouracil (fluorouracil), especially for people who are male, 60+ old, have been taking the drug for 1 - 6 months also take Oxaliplatin, and have Colon cancer.

The phase IV clinical study analyzes which people have Bronchiectasis when taking Fluorouracil. It is created by eHealthMe based on reports of 96,940 people who have side effects when taking Fluorouracil from the FDA, and is updated regularly.

What is Fluorouracil?

Fluorouracil has active ingredients of fluorouracil. It is often used in colon cancer metastatic. eHealthMe is studying from 97,087 Fluorouracil users. Check the latest studies of Fluorouracil.

What is Bronchiectasis?

Bronchiectasis (abnormal widening of the bronchi or their branches, causing a risk of infection) is found to be associated with 784 drugs and 858 conditions by eHealthMe. Check the latest studies of Bronchiectasis.

On Jul, 12, 2026

96,940 people reported to have side effects when taking Fluorouracil.
Among them, 17 people (0.02%) have Bronchiectasis.

Could Fluorouracil cause Bronchiectasis?

Among these 17 people:

How long have people been on Fluorouracil when they have Bronchiectasis? *

What is the gender of people who have Bronchiectasis when taking Fluorouracil? *

female: 47.06 %
male: 52.94 %

What is the age of people who have Bronchiectasis when taking Fluorouracil? *

What are other drugs people take besides Fluorouracil? *

Oxaliplatin: 6 people, 35.29%
Leucovorin Calcium: 4 people, 23.53%
Levoleucovorin Calcium: 3 people, 17.65%
Plavix: 2 people, 11.76%
Decadron: 2 people, 11.76%
Omeprazole: 2 people, 11.76%
Isosorbide Mononitrate: 2 people, 11.76%
Kytril: 2 people, 11.76%
Zyprexa: 1 person, 5.88%
Cytoxan: 1 person, 5.88%

What are other side effects people have besides Bronchiectasis? *

Interstitial Lung Disease: 9 people, 52.94%
Idiopathic Pulmonary Fibrosis (chronic lung disease): 7 people, 41.18%
Thrombocytopenia (decrease of platelets in blood): 4 people, 23.53%
Stomatitis (inflammation of mucous membrane of mouth): 4 people, 23.53%
Dyspnea (difficult or laboured breathing): 4 people, 23.53%
Respiratory Acidosis (respiratory failure or ventilatory failure, causes the ph of blood and other bodily fluids to decrease): 4 people, 23.53%
Pulmonary Embolism (blockage of the main artery of the lung): 3 people, 17.65%
Respiratory Distress (difficulty in breathing): 3 people, 17.65%
Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection): 3 people, 17.65%
Dermatitis Acneiform (dermatoses including acne vulgaris, rosacea, folliculitis, and perioral dermatitis): 3 people, 17.65%

What are the existing conditions these people have? *

Colon Cancer: 5 people, 29.41%
Stable Angina (a constant chest pain): 1 person, 5.88%
Rectal Cancer Metastatic (cancer of rectum spreads to other): 1 person, 5.88%
Nausea And Vomiting: 1 person, 5.88%
Metastasis (spreadable cancer to other organ from origin): 1 person, 5.88%
Metastases To Bone (cancer spreads to bone): 1 person, 5.88%
Insomnia (sleeplessness): 1 person, 5.88%
Immunodeficiency Common Variable: 1 person, 5.88%
Hyperlipidaemia (presence of excess lipids in the blood): 1 person, 5.88%
High Blood Pressure: 1 person, 5.88%

* Approximation only. Some reports may have incomplete information.

Do you take Fluorouracil and have Bronchiectasis?

- Check whether Bronchiectasis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Fluorouracil:

Fluorouracil (97,087 reports)

Bronchiectasis treatments and more:

Bronchiectasis (12,460 reports)

Browse all side effects of Fluorouracil:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Bronchiectasis:

Bronchiectasis (784 drugs)

Browse all the conditions that are associated with Bronchiectasis:

Bronchiectasis (858 conditions)

Related publications that referenced our studies

Lee JK, Lee J, Park SS, Heo EY, Park YS, Lee CH, Lee SM, Yoon HI, Yim JJ, Yoo CG, Chung HS, "Effect of inhalers on the development of haemoptysis in patients with non-cystic fibrosis bronchiectasis", The International Journal of Tuberculosis and Lung Disease, 2014 Mar .
Lee JK, Lee J, Park SS, Heo EY, Park YS, Lee CH, Lee SM, Yoon HI, Yim JJ, Yoo CG, Chung HS, "Effect of inhalers on the development of haemoptysis in patients with non-cystic fibrosis bronchiectasis", The International Journal of Tuberculosis and Lung Disease, 2014 Mar .

How the study uses the data?

The study uses data from the FDA. It is based on fluorouracil (the active ingredients of Fluorouracil) and Fluorouracil (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.