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Fluorouracil and Eye pain - a phase IV clinical study of FDA data

Summary:

Eye pain is reported as a side effect among people who take Fluorouracil (fluorouracil), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Methotrexate, and have Colorectal cancer metastatic.

The phase IV clinical study analyzes which people have Eye pain when taking Fluorouracil. It is created by eHealthMe based on reports of 96,940 people who have side effects when taking Fluorouracil from the FDA, and is updated regularly.

What is Fluorouracil?

Fluorouracil has active ingredients of fluorouracil. It is often used in colon cancer metastatic. eHealthMe is studying from 97,087 Fluorouracil users. Check the latest studies of Fluorouracil.

What is Eye pain?

Eye pain is found to be associated with 1,754 drugs and 2,465 conditions by eHealthMe. Check the latest studies of Eye pain.

On Apr, 23, 2026

96,940 people reported to have side effects when taking Fluorouracil.
Among them, 80 people (0.08%) have Eye pain.

Could Fluorouracil cause Eye pain?

Among these 80 people:

How long have people been on Fluorouracil when they have Eye pain? *

  • < 1 month: 66.67 %
  • 1 - 6 months: 26.67 %
  • 6 - 12 months: 6.67 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Eye pain when taking Fluorouracil? *

  • female: 72.97 %
  • male: 27.03 %

What is the age of people who have Eye pain when taking Fluorouracil? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 8.33 %
  • 50-59: 30.0 %
  • 60+: 61.67 %

What are other drugs people take besides Fluorouracil? *

  1. Methotrexate: 15 people, 18.75%
  2. Zometa: 11 people, 13.75%
  3. Accuretic: 10 people, 12.50%
  4. Gemzar: 10 people, 12.50%
  5. Neurontin: 10 people, 12.50%
  6. Zofran: 10 people, 12.50%
  7. Benadryl: 10 people, 12.50%
  8. Carboplatin: 10 people, 12.50%
  9. Cytoxan: 10 people, 12.50%
  10. Lorazepam: 10 people, 12.50%

What are other side effects people have besides Eye pain? *

  1. Chest Pain: 28 people, 35.00%
  2. Abdominal Pain: 21 people, 26.25%
  3. Headache (pain in head): 21 people, 26.25%
  4. Fatigue (feeling of tiredness): 21 people, 26.25%
  5. Nausea (feeling of having an urge to vomit): 21 people, 26.25%
  6. Diarrhea: 20 people, 25.00%
  7. Anaemia (lack of blood): 20 people, 25.00%
  8. Joint Pain: 20 people, 25.00%
  9. Back Pain: 19 people, 23.75%
  10. Mucosal Inflammation (infection of mucous membrane): 18 people, 22.50%

What are the existing conditions these people have? *

  1. Colorectal Cancer Metastatic (cancer of colon and rectal spreads to other parts): 20 people, 25.00%
  2. Neoplasm Malignant (cancer tumour): 15 people, 18.75%
  3. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 7 people, 8.75%
  4. Muscle Aches (muscle pain): 7 people, 8.75%
  5. Musculoskeletal Pain (pain affects the bones, muscles, ligaments, tendons, and nerves): 7 people, 8.75%
  6. Osteoporosis (bones weak and more likely to break): 7 people, 8.75%
  7. Joint Pain: 7 people, 8.75%
  8. Anaemia (lack of blood): 7 people, 8.75%
  9. Inflammation: 6 people, 7.50%
  10. Fever: 5 people, 6.25%

* Approximation only. Some reports may have incomplete information.

Do you take Fluorouracil and have Eye pain?

- Check whether Eye pain is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Fluorouracil:

Eye pain treatments and more:

How severe was Eye pain and when was it recovered:

Expand to all the drugs that have ingredients of fluorouracil:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Fluorouracil:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Eye pain:

Browse all the conditions that are associated with Eye pain:

How the study uses the data?

The study uses data from the FDA. It is based on fluorouracil (the active ingredients of Fluorouracil) and Fluorouracil (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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