Fluorouracil and Spinal cord compression - a phase IV clinical study of FDA data

Summary:

Spinal cord compression is reported as a side effect among people who take Fluorouracil (fluorouracil), especially for people who are female, 50-59 old, have been taking the drug for < 1 month also take Zometa, and have Colon cancer.

The phase IV clinical study analyzes which people have Spinal cord compression when taking Fluorouracil. It is created by eHealthMe based on reports of 96,940 people who have side effects when taking Fluorouracil from the FDA, and is updated regularly.

What is Fluorouracil?

Fluorouracil has active ingredients of fluorouracil. It is often used in colon cancer metastatic. eHealthMe is studying from 97,087 Fluorouracil users. Check the latest studies of Fluorouracil.

What is Spinal cord compression?

Spinal cord compression is found to be associated with 614 drugs and 599 conditions by eHealthMe. Check the latest studies of Spinal cord compression.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Sep, 02, 2026

96,940 people reported to have side effects when taking Fluorouracil.
Among them, 62 people (0.06%) have Spinal cord compression.

Could Fluorouracil cause Spinal cord compression?

Among these 62 people:

How long have people been on Fluorouracil when they have Spinal cord compression? *

  • < 1 month: 80 %
  • 1 - 6 months: 10 %
  • 6 - 12 months: 10 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Spinal cord compression when taking Fluorouracil? *

  • female: 65 %
  • male: 35 %

What is the age of people who have Spinal cord compression when taking Fluorouracil? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 2.63 %
  • 30-39: 5.26 %
  • 40-49: 15.79 %
  • 50-59: 63.16 %
  • 60+: 13.16 %

What are other drugs people take besides Fluorouracil? *

  1. Zometa: 21 people, 33.87%
  2. Nexium: 19 people, 30.65%
  3. Coumadin: 14 people, 22.58%
  4. Zofran: 13 people, 20.97%
  5. Amoxicillin: 13 people, 20.97%
  6. Gemzar: 13 people, 20.97%
  7. Aspirin: 13 people, 20.97%
  8. Lortab: 12 people, 19.35%
  9. Oxytocin: 12 people, 19.35%
  10. Oxycontin: 12 people, 19.35%

What are other side effects people have besides Spinal cord compression? *

  1. Anaemia (lack of blood): 22 people, 35.48%
  2. Neoplasm Progression (growth of tumour): 21 people, 33.87%
  3. Pain: 21 people, 33.87%
  4. Pleural Effusion (water on the lungs): 20 people, 32.26%
  5. Metastases To Spine (cancer spreads to spine): 19 people, 30.65%
  6. Joint Pain: 19 people, 30.65%
  7. Stress And Anxiety: 18 people, 29.03%
  8. Malignant Neoplasm Progression (cancer tumour came back): 18 people, 29.03%
  9. Fever: 18 people, 29.03%
  10. Thrombocytopenia (decrease of platelets in blood): 18 people, 29.03%

What are the existing conditions these people have? *

  1. Breast Cancer Female: 6 people, 9.68%
  2. Colon Cancer: 6 people, 9.68%
  3. Breast Cancer Metastatic: 5 people, 8.06%
  4. Colorectal Cancer Metastatic (cancer of colon and rectal spreads to other parts): 5 people, 8.06%
  5. Lung Adenocarcinoma (a form of non-small cell lung cancer): 5 people, 8.06%
  6. Breast Cancer: 3 people, 4.84%
  7. Pain In Jaw: 2 people, 3.23%
  8. Gastric Cancer Stage Iv (cancer cells have spread to distant organs): 1 person, 1.61%
  9. Constipation: 1 person, 1.61%
  10. Diabetes: 1 person, 1.61%

* Approximation only. Some reports may have incomplete information.

Do you take Fluorouracil and have Spinal cord compression?

- Check whether Spinal cord compression is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Fluorouracil:

Spinal cord compression treatments and more:

How severe was Spinal cord compression and when was it recovered:

Expand to all the drugs that have ingredients of fluorouracil:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Fluorouracil:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Spinal cord compression:

Browse all the conditions that are associated with Spinal cord compression:


How the study uses the data?

The study uses data from the FDA. It is based on fluorouracil (the active ingredients of Fluorouracil) and Fluorouracil (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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