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Fluoxetine and Chronic hepatitis - a phase IV clinical study of FDA data

Summary:

Chronic hepatitis is reported as a side effect among people who take Fluoxetine (fluoxetine hydrochloride), especially for people who are female, 60+ old, have been taking the drug for 6 - 12 months also take Keppra, and have Back pain.

The phase IV clinical study analyzes which people have Chronic hepatitis when taking Fluoxetine. It is created by eHealthMe based on reports of 94,370 people who have side effects when taking Fluoxetine from the FDA, and is updated regularly.

What is Fluoxetine?

Fluoxetine has active ingredients of fluoxetine hydrochloride. It is often used in depression. eHealthMe is studying from 98,826 Fluoxetine users. Check the latest studies of Fluoxetine.

What is Chronic hepatitis?

Chronic hepatitis (long lasting inflammation of liver) is found to be associated with 116 drugs and 354 conditions by eHealthMe. Check the latest studies of Chronic hepatitis.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 02, 2026

94,370 people reported to have side effects when taking Fluoxetine.
Among them, 14 people (0.01%) have Chronic hepatitis.

Could Fluoxetine cause Chronic hepatitis?

Among these 14 people:

How long have people been on Fluoxetine when they have Chronic hepatitis? *

  • < 1 month: 0.0 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 100 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Chronic hepatitis when taking Fluoxetine? *

  • female: 92.86 %
  • male: 7.14 %

What is the age of people who have Chronic hepatitis when taking Fluoxetine? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 42.86 %
  • 30-39: 0.0 %
  • 40-49: 14.29 %
  • 50-59: 0.0 %
  • 60+: 42.86 %

What are other drugs people take besides Fluoxetine? *

  1. Asmanex Twisthaler: 6 people, 42.86%
  2. Proair Hfa: 6 people, 42.86%
  3. Ibuprofen: 6 people, 42.86%
  4. Keppra: 6 people, 42.86%
  5. Tylenol W/ Codeine No. 3: 5 people, 35.71%
  6. Rebif: 2 people, 14.29%
  7. Zolpidem: 1 person, 7.14%
  8. Lactulose: 1 person, 7.14%
  9. Amlodipine: 1 person, 7.14%
  10. Carbamazepine: 1 person, 7.14%

What are other side effects people have besides Chronic hepatitis? *

  1. Overdose: 7 people, 50.00%
  2. Drug Administration Error: 6 people, 42.86%
  3. Urinary Tract Infection: 6 people, 42.86%
  4. Maternal Exposure During Pregnancy (use of substance during pregnancy): 6 people, 42.86%
  5. Ascites (accumulation of fluid in the abdominal cavity): 3 people, 21.43%
  6. Cardiac Arrest: 3 people, 21.43%
  7. Depressed Mood: 3 people, 21.43%
  8. Sepsis (a severe blood infection that can lead to organ failure and death): 3 people, 21.43%
  9. Arrhythmias (irregular heartbeat): 3 people, 21.43%
  10. Pneumonia: 3 people, 21.43%

What are the existing conditions these people have? *

  1. Postpartum Depression (depression suffered by a mother following childbirth): 6 people, 42.86%
  2. Dyspnea (difficult or laboured breathing): 6 people, 42.86%
  3. Back Pain: 6 people, 42.86%
  4. Pain: 3 people, 21.43%
  5. Thyroid Diseases: 2 people, 14.29%
  6. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 2 people, 14.29%
  7. Sinusitis (inflammation of sinus): 1 person, 7.14%
  8. Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 1 person, 7.14%
  9. Joint Pain: 1 person, 7.14%

* Approximation only. Some reports may have incomplete information.

Do you take Fluoxetine and have Chronic hepatitis?

- Check whether Chronic hepatitis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Fluoxetine:

Chronic hepatitis treatments and more:

How severe was Chronic hepatitis and when was it recovered:

Expand to all the drugs that have ingredients of fluoxetine hydrochloride:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Fluoxetine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Chronic hepatitis:

Browse all the conditions that are associated with Chronic hepatitis:

Related publications that referenced our studies

How the study uses the data?

The study uses data from the FDA. It is based on fluoxetine hydrochloride (the active ingredients of Fluoxetine) and Fluoxetine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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