Fluoxetine and Diffuse interstitial lung disease - a phase IV clinical study of FDA data

Summary:

Diffuse interstitial lung disease is reported as a side effect among people who take Fluoxetine (fluoxetine hydrochloride), especially for people who are female, 60+ old, also take Levothyroxine Sodium, and have Rheumatoid arthritis.

The phase IV clinical study analyzes which people have Diffuse interstitial lung disease when taking Fluoxetine. It is created by eHealthMe based on reports of 94,370 people who have side effects when taking Fluoxetine from the FDA, and is updated regularly.

What is Fluoxetine?

Fluoxetine has active ingredients of fluoxetine hydrochloride. It is often used in depression. eHealthMe is studying from 98,823 Fluoxetine users. Check the latest studies of Fluoxetine.

What is Diffuse interstitial lung disease?

Diffuse interstitial lung disease (group of lung diseases affecting the interstitium) is found to be associated with 232 drugs and 801 conditions by eHealthMe. Check the latest studies of Diffuse interstitial lung disease.



On Jul, 27, 2026

94,370 people reported to have side effects when taking Fluoxetine.
Among them, 22 people (0.02%) have Diffuse interstitial lung disease.

Could Fluoxetine cause Diffuse interstitial lung disease?

Among these 22 people:

What is the gender of people who have Diffuse interstitial lung disease when taking Fluoxetine? *

  • female: 90.48 %
  • male: 9.52 %

What is the age of people who have Diffuse interstitial lung disease when taking Fluoxetine? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 6.67 %
  • 30-39: 6.67 %
  • 40-49: 26.67 %
  • 50-59: 13.33 %
  • 60+: 46.67 %

What are other drugs people take besides Fluoxetine? *

  1. Acyclovir: 4 people, 18.18%
  2. Crestor: 4 people, 18.18%
  3. Levothyroxine Sodium: 4 people, 18.18%
  4. Acetaminophen: 3 people, 13.64%
  5. Morphine Sulfate: 3 people, 13.64%
  6. Diazepam: 3 people, 13.64%
  7. Etidronate Disodium: 3 people, 13.64%
  8. Furosemide: 3 people, 13.64%
  9. Clonidine: 3 people, 13.64%
  10. Humira: 3 people, 13.64%

What are other side effects people have besides Diffuse interstitial lung disease? *

  1. Interstitial Lung Disease: 7 people, 31.82%
  2. Pneumonia: 4 people, 18.18%
  3. Weakness: 3 people, 13.64%
  4. Pain: 3 people, 13.64%
  5. Dyspnea (difficult or laboured breathing): 3 people, 13.64%
  6. Fatigue (feeling of tiredness): 3 people, 13.64%
  7. Tremor (trembling or shaking movements in one or more parts of your body): 3 people, 13.64%
  8. Idiopathic Pulmonary Fibrosis (chronic lung disease): 3 people, 13.64%
  9. Respiratory Acidosis (respiratory failure or ventilatory failure, causes the ph of blood and other bodily fluids to decrease): 3 people, 13.64%
  10. Pneumocystis Jiroveci Infection (fungal infection of the lungs): 3 people, 13.64%

What are the existing conditions these people have? *

  1. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 4 people, 18.18%
  2. Glioblastoma Multiforme (most common and deadliest of malignant primary brain tumours in adults): 3 people, 13.64%
  3. Chronic Lymphocytic Leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 2 people, 9.09%
  4. Pleural Mesothelioma (cancer of the pleura, or the membrane that lines the lungs): 1 person, 4.55%
  5. Gastrointestinal Stromal Tumor: 1 person, 4.55%

* Approximation only. Some reports may have incomplete information.

Do you take Fluoxetine and have Diffuse interstitial lung disease?

- Check whether Diffuse interstitial lung disease is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Fluoxetine:

Diffuse interstitial lung disease treatments and more:

How severe was Diffuse interstitial lung disease and when was it recovered:

Expand to all the drugs that have ingredients of fluoxetine hydrochloride:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Fluoxetine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Diffuse interstitial lung disease:

Browse all the conditions that are associated with Diffuse interstitial lung disease:


How the study uses the data?

The study uses data from the FDA. It is based on fluoxetine hydrochloride (the active ingredients of Fluoxetine) and Fluoxetine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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