Fluoxetine and Hyporeflexia - a phase IV clinical study of FDA data

Summary:

Hyporeflexia is reported as a side effect among people who take Fluoxetine (fluoxetine hydrochloride), especially for people who are female, 10-19 old, have been taking the drug for < 1 month also take Amisulpride, and have Suicide attempt.

The phase IV clinical study analyzes which people have Hyporeflexia when taking Fluoxetine. It is created by eHealthMe based on reports of 94,370 people who have side effects when taking Fluoxetine from the FDA, and is updated regularly.

What is Fluoxetine?

Fluoxetine has active ingredients of fluoxetine hydrochloride. It is often used in depression. eHealthMe is studying from 98,823 Fluoxetine users. Check the latest studies of Fluoxetine.

What is Hyporeflexia?

Hyporeflexia (a condition of below normal or absent reflexes) is found to be associated with 448 drugs and 593 conditions by eHealthMe. Check the latest studies of Hyporeflexia.

On Jul, 19, 2026

94,370 people reported to have side effects when taking Fluoxetine.
Among them, 40 people (0.04%) have Hyporeflexia.

Among these 40 people:

How long have people been on Fluoxetine when they have Hyporeflexia? *

What is the gender of people who have Hyporeflexia when taking Fluoxetine? *

female: 84.21 %
male: 15.79 %

What is the age of people who have Hyporeflexia when taking Fluoxetine? *

What are other drugs people take besides Fluoxetine? *

What are other side effects people have besides Hyporeflexia? *

Nausea And Vomiting: 15 people, 37.50%
Electrocardiogram Qt Prolonged: 13 people, 32.50%
Cough: 13 people, 32.50%
Mydriasis (a dilation of the pupil): 12 people, 30.00%
Sopor (sleep): 11 people, 27.50%
Suicide Attempt: 8 people, 20.00%
Intestinal Ischaemia (decreased supply of oxygenated blood to the intestines): 6 people, 15.00%
General Physical Health Deterioration (weak health status): 6 people, 15.00%
Feeding Disorder (when children refuse to eat certain food groups): 6 people, 15.00%
Hepatotoxicity (chemical-driven liver damage): 5 people, 12.50%

What are the existing conditions these people have? *

Suicide Attempt: 6 people, 15.00%
High Blood Pressure: 4 people, 10.00%
Itching: 3 people, 7.50%
Short-Bowel Syndrome (a condition in which the body cannot absorb enough fluids and nutrients because part of the small intestine is missing): 2 people, 5.00%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 2 people, 5.00%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 2 people, 5.00%
Type 2 Diabetes: 1 person, 2.50%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 2.50%
Bladder Disorder: 1 person, 2.50%
Bleeding Disorders: 1 person, 2.50%

* Approximation only. Some reports may have incomplete information.

Do you take Fluoxetine and have Hyporeflexia?

- Check whether Hyporeflexia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Fluoxetine:

Fluoxetine (98,823 reports)

Hyporeflexia treatments and more:

Hyporeflexia (3,443 reports)

Browse all side effects of Fluoxetine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hyporeflexia:

Hyporeflexia (448 drugs)

Browse all the conditions that are associated with Hyporeflexia:

Hyporeflexia (593 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on fluoxetine hydrochloride (the active ingredients of Fluoxetine) and Fluoxetine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.