Fluoxetine and Retinal detachment - a phase IV clinical study of FDA data

Summary:

Retinal detachment is reported as a side effect among people who take Fluoxetine (fluoxetine hydrochloride), especially for people who are male, 50-59 old, have been taking the drug for < 1 month also take Solu-Medrol, and have Rheumatoid arthritis.

The phase IV clinical study analyzes which people have Retinal detachment when taking Fluoxetine. It is created by eHealthMe based on reports of 94,370 people who have side effects when taking Fluoxetine from the FDA, and is updated regularly.

What is Fluoxetine?

Fluoxetine has active ingredients of fluoxetine hydrochloride. It is often used in depression. eHealthMe is studying from 98,823 Fluoxetine users. Check the latest studies of Fluoxetine.

What is Retinal detachment?

Retinal detachment (a disorder of the eye in which the retina peels away from its underlying layer of support tissue) is found to be associated with 714 drugs and 1,007 conditions by eHealthMe. Check the latest studies of Retinal detachment.

On Jul, 17, 2026

94,370 people reported to have side effects when taking Fluoxetine.
Among them, 49 people (0.05%) have Retinal detachment.

Could Fluoxetine cause Retinal detachment?

Among these 49 people:

How long have people been on Fluoxetine when they have Retinal detachment? *

What is the gender of people who have Retinal detachment when taking Fluoxetine? *

female: 44.9 %
male: 55.1 %

What is the age of people who have Retinal detachment when taking Fluoxetine? *

What are other drugs people take besides Fluoxetine? *

What are other side effects people have besides Retinal detachment? *

Blindness: 11 people, 22.45%
Malaise (a feeling of general discomfort or uneasiness): 6 people, 12.24%
Pain In Extremity: 5 people, 10.20%
Hypoaesthesia (reduced sense of touch or sensation): 5 people, 10.20%
Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 5 people, 10.20%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 5 people, 10.20%
Nausea (feeling of having an urge to vomit): 5 people, 10.20%
Uveitis (inflammation of the uvea): 5 people, 10.20%
Weight Decreased: 5 people, 10.20%
Weakness: 5 people, 10.20%

What are the existing conditions these people have? *

Uveitis (inflammation of the uvea): 5 people, 10.20%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 5 people, 10.20%
Malignant Melanoma (skin cancer rises from melancytes): 4 people, 8.16%
Osteoporosis (bones weak and more likely to break): 3 people, 6.12%
Joint Pain: 2 people, 4.08%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 4.08%
Vasodilatation (widening of blood vessels resulting from relaxation of smooth muscle cells within the vessel walls): 2 people, 4.08%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 2 people, 4.08%
Cytomegalovirus Chorioretinitis (infection of choroid and retina of the eye from virus): 2 people, 4.08%
Cytomegalovirus Viraemia (cytomegalo virus in blood stream): 2 people, 4.08%

* Approximation only. Some reports may have incomplete information.

Do you take Fluoxetine and have Retinal detachment?

- Check whether Retinal detachment is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Fluoxetine:

Fluoxetine (98,823 reports)

Browse all side effects of Fluoxetine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Retinal detachment:

Retinal detachment (714 drugs)

Browse all the conditions that are associated with Retinal detachment:

Retinal detachment (1,007 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on fluoxetine hydrochloride (the active ingredients of Fluoxetine) and Fluoxetine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.