Fluoxetine and Somatisation disorder - a phase IV clinical study of FDA data

Summary:

Somatisation disorder is reported as a side effect among people who take Fluoxetine (fluoxetine hydrochloride), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Zopiclone, and have Insomnia.

The phase IV clinical study analyzes which people have Somatisation disorder when taking Fluoxetine. It is created by eHealthMe based on reports of 94,370 people who have side effects when taking Fluoxetine from the FDA, and is updated regularly.

What is Fluoxetine?

Fluoxetine has active ingredients of fluoxetine hydrochloride. It is often used in depression. eHealthMe is studying from 98,826 Fluoxetine users. Check the latest studies of Fluoxetine.

What is Somatisation disorder?

Somatisation disorder (a long-term (chronic) condition in which a person has physical symptoms that involve more than one part of the body) is found to be associated with 57 drugs and 148 conditions by eHealthMe. Check the latest studies of Somatisation disorder.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 31, 2026

94,370 people reported to have side effects when taking Fluoxetine.
Among them, 12 people (0.01%) have Somatisation disorder.

Could Fluoxetine cause Somatisation disorder?

Among these 12 people:

How long have people been on Fluoxetine when they have Somatisation disorder? *

What is the gender of people who have Somatisation disorder when taking Fluoxetine? *

female: 90.91 %
male: 9.09 %

What is the age of people who have Somatisation disorder when taking Fluoxetine? *

What are other drugs people take besides Fluoxetine? *

What are other side effects people have besides Somatisation disorder? *

Agitation (state of anxiety or nervous excitement): 11 people, 91.67%
Malaise (a feeling of general discomfort or uneasiness): 11 people, 91.67%
Dizziness: 11 people, 91.67%
Feeling Abnormal: 11 people, 91.67%
Depressed Mood: 10 people, 83.33%
Negative Thoughts: 10 people, 83.33%
Emotional Distress: 10 people, 83.33%
Dry Eyes (lack of adequate tears): 10 people, 83.33%
Asthenopia (eyestrain-tiredness of the eyes caused by prolonged close work by a person with an uncorrected vision problem): 10 people, 83.33%
Panic Reaction: 10 people, 83.33%

What are the existing conditions these people have? *

Insomnia (sleeplessness): 8 people, 66.67%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

Do you take Fluoxetine and have Somatisation disorder?

- Check whether Somatisation disorder is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Fluoxetine:

Fluoxetine (98,826 reports)

Browse all side effects of Fluoxetine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Somatisation disorder:

Somatisation disorder (57 drugs)

Browse all the conditions that are associated with Somatisation disorder:

Somatisation disorder (148 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on fluoxetine hydrochloride (the active ingredients of Fluoxetine) and Fluoxetine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.