Folate and Arthropathy - a phase IV clinical study of FDA data

Summary:

Arthropathy is reported as a side effect among people who take Folate (folic acid), especially for people who are female, 60+ old, also take Vitamin C, and have Multiple myeloma.

The phase IV clinical study analyzes which people have Arthropathy when taking Folate. It is created by eHealthMe based on reports of 5,953 people who have side effects when taking Folate from the FDA, and is updated regularly.

What is Folate?

Folate has active ingredients of folic acid. It is often used in rheumatoid arthritis. eHealthMe is studying from 6,546 Folate users. Check the latest studies of Folate.

What is Arthropathy?

Arthropathy is found to be associated with 1,603 drugs and 1,685 conditions by eHealthMe. Check the latest studies of Arthropathy.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 27, 2026

5,953 people reported to have side effects when taking Folate.
Among them, 41 people (0.69%) have Arthropathy.

Among these 41 people:

What is the gender of people who have Arthropathy when taking Folate? *

female: 57.5 %
male: 42.5 %

What is the age of people who have Arthropathy when taking Folate? *

What are other drugs people take besides Folate? *

What are other side effects people have besides Arthropathy? *

Joint Pain: 20 people, 48.78%
Swelling: 18 people, 43.90%
Osteoarthritis (a joint disease caused by cartilage loss in a joint): 17 people, 41.46%
Urinary Tract Infection: 16 people, 39.02%
Weight Decreased: 15 people, 36.59%
Back Pain: 15 people, 36.59%
Osteomyelitis (infection of bone): 15 people, 36.59%
Drowsiness: 14 people, 34.15%
Bursitis (inflammation of a bursa, typically one in the knee, elbow, or shoulder): 14 people, 34.15%
Renal Impairment (severely reduced kidney function): 14 people, 34.15%

What are the existing conditions these people have? *

Multiple Myeloma (cancer of the plasma cells): 12 people, 29.27%
Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 4 people, 9.76%
Infection: 3 people, 7.32%
Ulcerative Colitis (inflammatory bowel disease (ibd). it causes swelling, ulcerations, and loss of function of the large intestine): 3 people, 7.32%
Diabetes: 2 people, 4.88%
Immunodeficiency Common Variable: 2 people, 4.88%
Bladder Disorder: 2 people, 4.88%
Reflux Oesophagitis (an oesophageal mucosal injury that occurs of gastric contents into the oesophagus): 1 person, 2.44%
Pain In Extremity: 1 person, 2.44%
Blood Homocysteine Decreased: 1 person, 2.44%

* Approximation only. Some reports may have incomplete information.

Do you take Folate and have Arthropathy?

- Check whether Arthropathy is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Folate:

Folate (6,546 reports)

Arthropathy treatments and more:

Arthropathy (75,984 reports)

Browse all side effects of Folate:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Arthropathy:

Arthropathy (1,603 drugs)

Browse all the conditions that are associated with Arthropathy:

Arthropathy (1,685 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on folic acid (the active ingredients of Folate) and Folate (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.