Folate and Sciatica - a phase IV clinical study of FDA data

Summary:

Sciatica is reported as a side effect among people who take Folate (folic acid), especially for people who are female, 40-49 old, also take Vitamin B12, and have Anaemia.

The phase IV clinical study analyzes which people have Sciatica when taking Folate. It is created by eHealthMe based on reports of 5,953 people who have side effects when taking Folate from the FDA, and is updated regularly.

What is Folate?

Folate has active ingredients of folic acid. It is often used in rheumatoid arthritis. eHealthMe is studying from 6,546 Folate users. Check the latest studies of Folate.

What is Sciatica?

Sciatica (a set of symptoms including pain caused by general compression or irritation of one of five spinal nerve roots of each sciatic nerve) is found to be associated with 1,137 drugs and 1,433 conditions by eHealthMe. Check the latest studies of Sciatica.

On Jul, 14, 2026

5,953 people reported to have side effects when taking Folate.
Among them, 25 people (0.42%) have Sciatica.

Among these 25 people:

What is the gender of people who have Sciatica when taking Folate? *

female: 95 %
male: 5 %

What is the age of people who have Sciatica when taking Folate? *

What are other drugs people take besides Folate? *

Vitamin B12: 20 people, 80.00%
Magnesium: 18 people, 72.00%
Aimovig: 17 people, 68.00%
Topiramate: 12 people, 48.00%
Simvastatin: 10 people, 40.00%
Coenzyme Q10: 10 people, 40.00%
Vitamin B2: 9 people, 36.00%
Propranolol Hydrochloride: 7 people, 28.00%
Ubidecarenone: 6 people, 24.00%
Riboflavin: 4 people, 16.00%

What are other side effects people have besides Sciatica? *

Diarrhea: 23 people, 92.00%
Pain In Extremity: 22 people, 88.00%
Drug Ineffective: 22 people, 88.00%
Fatigue (feeling of tiredness): 22 people, 88.00%
Muscle Spasms (muscle contraction): 22 people, 88.00%
Cardiac Disorder: 21 people, 84.00%
Red Cell Distribution Width Increased: 21 people, 84.00%
Renal Pain (kidney pain): 21 people, 84.00%
Constipation: 21 people, 84.00%
Serotonin Syndrome (occurs when two drugs that affect the body's level of serotonin are taken together at the same time): 21 people, 84.00%

What are the existing conditions these people have? *

Migraine (headache): 21 people, 84.00%
Anaemia (lack of blood): 21 people, 84.00%
Sleep Disorder: 2 people, 8.00%
Stress And Anxiety: 1 person, 4.00%
Restless Leg Syndrome (a powerful urge to move your legs): 1 person, 4.00%
Pain: 1 person, 4.00%
Neuralgia (pain in one or more nerves): 1 person, 4.00%
Multiple Myeloma (cancer of the plasma cells): 1 person, 4.00%
Middle Insomnia (difficulty returning to sleep after awakening either in the middle of the night): 1 person, 4.00%
Depression: 1 person, 4.00%

* Approximation only. Some reports may have incomplete information.

Do you take Folate and have Sciatica?

- Check whether Sciatica is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Folate:

Folate (6,546 reports)

Sciatica treatments and more:

Sciatica (28,509 reports)

Browse all side effects of Folate:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Sciatica:

Sciatica (1,137 drugs)

Browse all the conditions that are associated with Sciatica:

Sciatica (1,433 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on folic acid (the active ingredients of Folate) and Folate (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.