Folvite and Insomnia exacerbated - a phase IV clinical study of FDA data

Summary:

Insomnia exacerbated is reported as a side effect among people who take Folvite (folic acid), especially for people who are male, 60+ old, also take Aldactone, and have Rheumatoid arthritis.

The phase IV clinical study analyzes which people have Insomnia exacerbated when taking Folvite. It is created by eHealthMe based on reports of 2,509 people who have side effects when taking Folvite from the FDA, and is updated regularly.

What is Folvite?

Folvite has active ingredients of folic acid. eHealthMe is studying from 2,529 Folvite users. Check the latest studies of Folvite.

What is Insomnia exacerbated?

Insomnia exacerbated (severe sleeplessness) is found to be associated with 2,683 drugs and 976 conditions by eHealthMe. Check the latest studies of Insomnia exacerbated.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 30, 2026

2,509 people reported to have side effects when taking Folvite.
Among them, 34 people (1.36%) have Insomnia exacerbated.

Could Folvite cause Insomnia exacerbated?

Among these 34 people:

What is the gender of people who have Insomnia exacerbated when taking Folvite? *

female: 44.12 %
male: 55.88 %

What is the age of people who have Insomnia exacerbated when taking Folvite? *

What are other drugs people take besides Folvite? *

What are other side effects people have besides Insomnia exacerbated? *

Pain: 14 people, 41.18%
Nausea (feeling of having an urge to vomit): 12 people, 35.29%
Joint Pain: 10 people, 29.41%
Itching: 10 people, 29.41%
Weakness: 10 people, 29.41%
Feeling Abnormal: 9 people, 26.47%
Drug Ineffective: 9 people, 26.47%
Malaise (a feeling of general discomfort or uneasiness): 9 people, 26.47%
Fatigue (feeling of tiredness): 9 people, 26.47%
Oedema Peripheral (superficial swelling): 8 people, 23.53%

What are the existing conditions these people have? *

Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 7 people, 20.59%
Pain: 5 people, 14.71%
Psoriasis (immune-mediated disease that affects the skin): 5 people, 14.71%
Muscle Spasms (muscle contraction): 5 people, 14.71%
Hepatic Failure (liver failure): 4 people, 11.76%
Hepatic Encephalopathy (spectrum of neuropsychiatric abnormalities in patients with liver failure): 3 people, 8.82%
Fibromyalgia (a long-term condition which causes pain all over the body): 3 people, 8.82%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 8.82%
Wheezing (a high-pitched whistling sound made while you breath): 3 people, 8.82%
Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 3 people, 8.82%

* Approximation only. Some reports may have incomplete information.

Do you take Folvite and have Insomnia exacerbated?

- Check whether Insomnia exacerbated is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Folvite:

Folvite (2,529 reports)

Browse all side effects of Folvite:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Insomnia exacerbated:

Insomnia exacerbated (2,683 drugs)

Browse all the conditions that are associated with Insomnia exacerbated:

Insomnia exacerbated (976 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on folic acid (the active ingredients of Folvite) and Folvite (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.